Hepatitis B

Hepatitis B is a serious disease caused by a virus that attacks the liver. The virus, which is called hepatitis B virus (HBV), can cause lifelong infection, cirrhosis (scarring) of the liver, liver cancer, liver failure, and death. Transmission occurs when blood or body fluids from an infected person enter the body of a person who is not immune.

Vaccination: is given as three injections. (0, 1, 6 month)

Protection: is about 10 years after full vaccination.

Side effects:

• Cold or flu-like symptoms

hepb Resource:

The effects of booster vaccination of hepatitis B vaccine on anti-HBV surface antigen negative children 11-15 years after primary vaccination.
Yao J, Ren J, Shen L, Chen Y, Liang X, Cui F, Li Q, Jiang Z, Wang F.
Hum Vaccin. 2011 Oct;7(10):1055-9. Epub 2011 Oct 1
National and state vaccination coverage among children aged 19-35 months--United States, 2010.
Centers for Disease Control and Prevention (CDC).
MMWR Morb Mortal Wkly Rep. 2011 Sep 2;60(34):1157-63
Co-administration of human papillomavirus-16/18 AS04-adjuvanted vaccine with hepatitis B vaccine: randomized study in healthy girls.
Schmeink CE, Bekkers RL, Josefsson A, Richardus JH, Berndtsson Blom K, David MP, Dobbelaere K, Descamps D.
Vaccine. 2011 Nov 15;29(49):9276-83. Epub 2011 Aug 19
Hepatitis B vaccination coverage among high-risk adults 18-49 years, U.S., 2009.
Lu PJ, Byrd KK, Murphy TV, Weinbaum C.
Vaccine. 2011 Sep 16;29(40):7049-57. Epub 2011 Jul 22
Combined Haemophilus Influenzae type B-Neisseria meningitidis serogroup C vaccine is immunogenic and well tolerated in preterm infants when coadministered with other routinely recommended vaccines.
Omeñaca F, Arístegui J, Tejedor JC, Moreno-Perez D, Ruiz-Contreras J, Merino JM, Muro Brussi M, Sánchez-Tamayo T, Castro Fernandez J, Cabanillas L, Peddiraju K, Mesaros N, Miller JM.
Pediatr Infect Dis J. 2011 Nov;30(11):e216-24
Randomized trial of the immunogenicity and safety of the Hepatitis B vaccine given in an accelerated schedule coadministered with the human papillomavirus type 16/18 AS04-adjuvanted cervical cancer vaccine.
Leroux-Roels G, Haelterman E, Maes C, Levy J, De Boever F, Licini L, David MP, Dobbelaere K, Descamps D.
Clin Vaccine Immunol. 2011 Sep;18(9):1510-8. Epub 2011 Jul 6
Changes in hepatitis A and B vaccination rates in adult patients with chronic liver diseases and diabetes in the U.S. population.
Younossi ZM, Stepanova M.
Hepatology. 2011 Oct;54(4):1167-78. doi: 10.1002/hep.24510. Epub 2011 Aug 31
Vaccination coverage among children in kindergarten--United States, 2009-10 school year.
Centers for Disease Control and Prevention (CDC).
MMWR Morb Mortal Wkly Rep. 2011 Jun 3;60(21):700-4. Erratum in: MMWR Morb Mortal Wkly Rep. 2011 Jun 17;60(23):787.
Assessing completeness of perinatal hepatitis B virus infection reporting through comparison of immunization program and surveillance data--United States.
Centers for Disease Control and Prevention (CDC).
MMWR Morb Mortal Wkly Rep. 2011 Apr 8;60(13):410-3
Immunogenicity and safety of an indigenously manufactured reconstituted pentavalent (DTwP-HBV+Hib) vaccine in comparison with a foreign competitor following primary and booster immunization in Indian children.
Sharma HJ, Yadav S, Lalwani SK, Kapre SV, Jadhav SS, Chakravarty A, Parekh SS, Palkar S, Bhardwaj SH, Namjoshi GS, Verma V.
Hum Vaccin. 2011 Apr;7(4):451-7. Epub 2011 Apr 1
Private-sector vaccine purchase costs and insurer payments: a disincentive for using combination vaccines?
Clark SJ, Cowan AE, Freed GL.
Hum Vaccin. 2011 Apr;7(4):426-8. Epub 2011 Apr 1
Sustaining GAVI-supported vaccine introductions in resource-poor countries.
Zuber PL, El-Ziq I, Kaddar M, Ottosen AE, Rosenbaum K, Shirey M, Kamara L, Duclos P.
Vaccine. 2011 Apr 12;29(17):3149-54. Epub 2011 Feb 24
Co-administration of a novel Haemophilus influenzae type b and Neisseria meningitidis serogroups C and Y-tetanus toxoid conjugate vaccine does not interfere with the immune response to antigens contained in infant vaccines routinely used in the United States.
Marshall GS, Marchant CD, Blatter M, Friedland LR, Aris E, Miller JM.
Hum Vaccin. 2011 Feb;7(2):258-64. Epub 2011 Feb 1
[Study on the immunization coverage and effects of hepatitis B vaccine in the 20 - 59 years-old population in Guangzhou city.]
Liang JH, Wang M, Liu JH, Cai YS, Xu JX.
Zhonghua Liu Xing Bing Xue Za Zhi. 2010 Dec;31(12):1336-1339. Chinese.
Identifying long-term memory B-cells in vaccinated children despite waning antibody levels specific for Bordetella pertussis proteins.
Hendrikx LH, Oztürk K, de Rond LG, Veenhoven RH, Sanders EA, Berbers GA, Buisman AM.
Vaccine. 2011 Feb 4;29(7):1431-7. Epub 2010 Dec 25
Is chronic hepatitis B being undertreated in the United States?
Cohen C, Holmberg SD, McMahon BJ, Block JM, Brosgart CL, Gish RG, London WT, Block TM.
J Viral Hepat. 2011 Jun;18(6):377-83. doi: 10.1111/j.1365-2893.2010.01401.x. Epub 2010 Dec 8. Review
Financial barriers to the adoption of combination vaccines by pediatricians.
Gidengil CA, Dutta-Linn MM, Messonnier ML, Rusinak D, Lieu TA.
Arch Pediatr Adolesc Med. 2010 Dec;164(12):1138-44
Immunogenicity and reactogenicity of a combined fully liquid DTPw-HepB-Hib pentavalent vaccine in healthy infants: no clinically relevant impact of a birth dose of hepatitis B vaccine.
Gentile A, Umido V, Czerniuk P, Nacul J, Seigelchifer M, Hilbert AK, Yela U, Herzog C, Aeberhard U, Spyr C.
Int J Infect Dis. 2011 Jan;15(1):e24-9. Epub 2010 Nov 18
Global routine vaccination coverage, 2009.
Centers for Disease Control and Prevention (CDC).
MMWR Morb Mortal Wkly Rep. 2010 Oct 29;59(42):1367-71
Safety and immunogenicity of a booster dose of the 10-valent pneumococcal nontypeable Haemophilus influenzae protein D conjugate vaccine coadministered with DTPw-HBV/Hib and poliovirus vaccines.
Bermal N, Szenborn L, Edison A, Hernandez M, Pejcz J, Majda-Stanislawska E, Gatchalian S, Fanic A, Dieussaert I, Schuerman L.
Pediatr Infect Dis J. 2011 Jan;30(1):69-72
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