Hepatitis B

Hepatitis B is a serious disease caused by a virus that attacks the liver. The virus, which is called hepatitis B virus (HBV), can cause lifelong infection, cirrhosis (scarring) of the liver, liver cancer, liver failure, and death. Transmission occurs when blood or body fluids from an infected person enter the body of a person who is not immune.

Vaccination: is given as three injections. (0, 1, 6 month)

Protection: is about 10 years after full vaccination.

Side effects:

• Cold or flu-like symptoms

hepb Resource:

Pentavalent DTP vaccine: Need to be incorporated in the vaccination program of India.
Verma R, Khanna P, Chawla S.
Hum Vaccin Immunother. 2013 Apr 9;9(7). [Epub ahead of print
Strategies to prevent hepatitis B virus infection in China: Immunization, screening, and standard medical practices.
Zhang CY, Zhong YS, Guo LP.
Biosci Trends. 2013 Feb;7(1):7-12
Hepatitis A vaccination coverage among adults 18-49 years traveling to a country of high or intermediate endemicity, United States.
Lu PJ, Byrd KK, Murphy TV.
Vaccine. 2013 May 1;31(19):2348-57. doi: 10.1016/j.vaccine.2013.03.011. Epub 2013 Mar 21
The effects of booster vaccination on hepatitis B vaccine in anti-HBs negative infants of HBsAg-positive mothers after primary vaccination.
Gu H, Yao J, Zhu W, Lv H, Cheng S, Ling L, Xia S, Chen Y.
Hum Vaccin Immunother. 2013 Feb 19;9(6). [Epub ahead of print
Suppression of AKT anti-apoptotic signaling by a novel drug candidate results in growth arrest and apoptosis of hepatocellular carcinoma cells.
Cuconati A, Mills C, Goddard C, Zhang X, Yu W, Guo H, Xu X, Block TM.
PLoS One. 2013;8(1):e54595. doi: 10.1371/journal.pone.0054595. Epub 2013 Jan 23
The feasibility of using mobile-phone based SMS reminders and conditional cash transfers to improve timely immunization in rural Kenya.
Wakadha H, Chandir S, Were EV, Rubin A, Obor D, Levine OS, Gibson DG, Odhiambo F, Laserson KF, Feikin DR.
Vaccine. 2013 Jan 30;31(6):987-93. doi: 10.1016/j.vaccine.2012.11.093. Epub 2012 Dec 13
Safety and immunogenicity of a hexavalent vaccine administered at 2, 4 and 6 months of age with or without a heptavalent pneumococcal conjugate vaccine: a randomized, open-label study.
Tapiéro B, Halperin SA, Dionne M, Meekison W, Diaz-Mitoma F, Zickler P, Rubin E, Embree J, Bhuyan P, Lee AW, Li M, Tomovici A.
Pediatr Infect Dis J. 2013 Jan;32(1):54-61. doi: 10.1097/INF.0b013e3182717edf
Pricing strategies for combination pediatric vaccines based on the lowest overall cost formulary.
Behzad B, Jacobson SH, Sewell EC.
Expert Rev Vaccines. 2012 Oct;11(10):1189-97. doi: 10.1586/erv.12.97
[Study on antibody response to revaccination of epatitis B vaccine among firstly low-response adults].
Feng Y, Yan BY, Zhang L, Lü JJ, Liu JY, Gong XH, Cui FQ, Liang XF, Chen SY, Xu AQ.
Zhonghua Yu Fang Yi Xue Za Zhi. 2012 Sep;46(9):813-7. Chinese.
Antibody responses to vaccination among South African HIV-exposed and unexposed uninfected infants during the first 2 years of life.
Reikie BA, Naidoo S, Ruck CE, Slogrove AL, de Beer C, la Grange H, Adams RC, Ho K, Smolen K, Speert DP, Cotton MF, Preiser W, Esser M, Kollmann TR.
Clin Vaccine Immunol. 2013 Jan;20(1):33-8. doi: 10.1128/CVI.00557-12. Epub 2012 Oct 31
Introduction of Haemophilus influenzae type b (Hib) as pentavalent(DPT-HepB-Hib) vaccine in two states of India.
Gupta SK, Sosler S, Lahariya C.
Indian Pediatr. 2012 Sep;49(9):707-9. No abstract available.
Postvaccination serologic testing results for infants aged ≤24 months exposed to hepatitis B virus at birth: United States, 2008-2011.
Centers for Disease Control and Prevention (CDC).
MMWR Morb Mortal Wkly Rep. 2012 Sep 28;61:768-71
National, state, and local area vaccination coverage among children aged 19-35 months--United States, 2011.
Centers for Disease Control and Prevention (CDC).
MMWR Morb Mortal Wkly Rep. 2012 Sep 7;61:689-96
An update after 16 years of hepatitis B vaccination in South Africa.
Burnett RJ, Kramvis A, Dochez C, Meheus A.
Vaccine. 2012 Sep 7;30 Suppl 3:C45-51. doi: 10.1016/j.vaccine.2012.02.021. Review
Implementing new health interventions in developing countries: why do we lose a decade or more?
Brooks A, Smith TA, de Savigny D, Lengeler C.
BMC Public Health. 2012 Aug 21;12:683. doi: 10.1186/1471-2458-12-683
Development and introduction of a ready-to-use pediatric pentavalent vaccine to meet and sustain the needs of developing countries--Quinvaxem®: the first 5 years.
Schmid DA, Macura-Biegun A, Rauscher M.
Vaccine. 2012 Sep 28;30(44):6241-8. doi: 10.1016/j.vaccine.2012.07.088. Epub 2012 Aug 10. Review
Lot-to-lot consistency study of the fully liquid pentavalent DTwP-HepB-Hib vaccine Quinvaxem (®) demonstrating clinical equivalence, suitability of the vaccine as a booster and concomitant administration with measles vaccine.
Aspinall S, Traynor D, Bedford P, Hartmann K.
Hum Vaccin Immunother. 2012 Aug;8(8):1109-18. doi: 10.4161/hv.21095. Epub 2012 Aug 1
Risk factors for low vaccination coverage among Roma children in disadvantaged settlements in Belgrade, Serbia.
Stojanovski K, McWeeney G, Emiroglu N, Ostlin P, Koller T, Licari L, Kaluski DN.
Vaccine. 2012 Aug 10;30(37):5459-63. doi: 10.1016/j.vaccine.2012.06.072. Epub 2012 Jul 6
Timing of hepatitis B vaccination and impact of non-simultaneous vaccination with DTP vaccine following introduction of a hepatitis B birth dose in the Philippines.
Wallace AS, Sobel H, Ryman TK, Mantaring JB 3rd, Silvestre M, Thorley M, Ducusin J, Nyunt-U S.
J Public Health Policy. 2012 Aug;33(3):368-81
[Comparison on the antibody response after primary immunization of 5 µg and 10 µg hepatitis B vaccine made by recombinant DNA techniques among newborns].
Zhang L, Zhang W, Zhai XJ, Li YP, Li J, Yan BY, Li YT, Zhu FC, Huang T, Li LQ, Gong XH, Cui FQ, Liang XF, Xu AQ.
Zhonghua Liu Xing Bing Xue Za Zhi. 2012 Mar;33(3):305-8. Chinese.
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