Cholera

Indications: Vaccination provides protection against enteric disease, particularly diarrhoea, caused by ETEC or cholera.

Vaccination: vaccine is given as granulate, which is swallowed.

Protection: Vaccination gives protection against cholera and ETEC for 6 month, there after the protecting fades.

Side effects: does normally not occur.  

Cholera Vaccination Resource:

Evaluation and use of surveillance system data toward the identification of high-risk areas for potential cholera vaccination: a case study from Niger.
Guerra J, Mayana B, Djibo A, Monzo ML, Llosa AE, Grais RF.
BMC Res Notes. 2012 May 14;5(1):231. [Epub ahead of print
Vaccines against mucosal infections.
Holmgren J, Svennerholm AM.
Curr Opin Immunol. 2012 May 11. [Epub ahead of print
Prophylactic and therapeutic efficacy of the epitope vaccine CTB-UA against Helicobacter pylori infection in a BALB/c mice model.
Guo L, Liu K, Xu G, Li X, Tu J, Tang F, Xing Y, Xi T.
Appl Microbiol Biotechnol. 2012 May 10. [Epub ahead of print
Loss of Sialic Acid Binding Domain Redirects Protein σ1 to Enhance M Cell-Directed Vaccination.
Zlotkowska D, Maddaloni M, Riccardi C, Walters N, Holderness K, Callis G, Rynda-Apple A, Pascual DW.
PLoS One. 2012;7(4):e36182. Epub 2012 Apr 30
Alkyl hydroperoxide reductase: A candidate Helicobacter pylori vaccine.
O'Riordan AA, Morales VA, Mulligan L, Faheem N, Windle HJ, Kelleher DP.
Vaccine. 2012 Jun 6;30(26):3876-84. Epub 2012 Apr 15
Haiti launches vaccination campaign against cholera after much debate.
Hawkes N.
BMJ. 2012 Apr 16;344:e2748. doi: 10.1136/bmj.e2748. No abstract available.
Memory B Cell and Other Immune Responses in Children Receiving Two Doses of an Oral Killed Cholera Vaccine Compared to Responses following Natural Cholera Infection in Bangladesh.
Leung DT, Rahman MA, Mohasin M, Patel SM, Aktar A, Khanam F, Uddin T, Riyadh MA, Saha A, Alam MM, Chowdhury F, Khan AI, Charles R, Larocque R, Harris JB, Calderwood SB, Qadri F, Ryan ET.
Clin Vaccine Immunol. 2012 May;19(5):690-8. Epub 2012 Mar 21
M cell targeting by a Claudin 4 targeting peptide can enhance mucosal IgA responses.
Lo DD, Ling J, Holly Eckelhoefer A.
BMC Biotechnol. 2012 Mar 13;12:7
Transcutaneous immunization with a Vibrio cholerae O1 Ogawa synthetic hexasaccharide conjugate following oral whole-cell cholera vaccination boosts vibriocidal responses and induces protective immunity in mice.
Tarique AA, Kalsy A, Arifuzzaman M, Rollins SM, Charles RC, Leung DT, Harris JB, Larocque RC, Sheikh A, Bhuiyan MS, Saksena R, Clements JD, Calderwood SB, Qadri F, Kovác P, Ryan ET.
Clin Vaccine Immunol. 2012 Apr;19(4):594-602. Epub 2012 Feb 22
Bacteria and their toxins tamed for immunotherapy.
Adkins I, Holubova J, Kosova M, Sadilkova L.
Curr Pharm Biotechnol. 2012 Feb 14. [Epub ahead of print
Integrating health promotion and disease prevention interventions with vaccination in Honduras.
Molina-Aguilera IB, Mendoza-Rodríguez LO, Palma-Ríos MA, Danovaro-Holliday MC.
J Infect Dis. 2012 Mar;205 Suppl 1:S77-81. Review
Cholera toxin activates nonconventional adjuvant pathways that induce protective CD8 T-cell responses after epicutaneous vaccination.
Olvera-Gomez I, Hamilton SE, Xiao Z, Guimaraes CP, Ploegh HL, Hogquist KA, Wang L, Jameson SC.
Proc Natl Acad Sci U S A. 2012 Feb 7;109(6):2072-7. Epub 2012 Jan 23
Haiti prepares for cholera vaccination but concerns remain.
Adams P.
Lancet. 2012 Jan 7;379(9810):16. No abstract available. Erratum in: Lancet. 2012 Mar 24;379(9821):1102.
Mucosal vaccination increases local chemokine production attracting immune cells to the stomach mucosa of Helicobacter pylori infected mice.
Flach CF, Mozer M, Sundquist M, Holmgren J, Raghavan S.
Vaccine. 2012 Feb 21;30(9):1636-43. Epub 2012 Jan 9
Sublingual immunization with adenovirus F protein-based vaccines stimulates protective immunity against botulinum neurotoxin A intoxication.
Jun S, Clapp B, Zlotkowska D, Hoyt T, Holderness K, Maddaloni M, Pascual DW.
Int Immunol. 2012 Feb;24(2):117-28. Epub 2011 Dec 29
Vaccination with M2e-based multiple antigenic peptides: characterization of the B cell response and protection efficacy in inbred and outbred mice.
Wolf AI, Mozdzanowska K, Williams KL, Singer D, Richter M, Hoffmann R, Caton AJ, Otvos L, Erikson J.
PLoS One. 2011;6(12):e28445. Epub 2011 Dec 13
An overview of cholera vaccines and their public health implications.
Desai SN, Clemens JD.
Curr Opin Pediatr. 2012 Feb;24(1):85-91. Review
Immunological features and the ability of inhibitory effects on enzymatic activity of an epitope vaccine composed of cholera toxin B subunit and B cell epitope from Helicobacter pylori urease A subunit.
Guo L, Li X, Tang F, He Y, Xing Y, Deng X, Xi T.
Appl Microbiol Biotechnol. 2012 Mar;93(5):1937-45. Epub 2011 Dec 2
Social and cultural determinants of anticipated acceptance of an oral cholera vaccine prior to a mass vaccination campaign in Zanzibar.
Schaetti C, Chaignat CL, Hutubessy R, Khatib AM, Ali SM, Schindler C, Weiss MG.
Hum Vaccin. 2011 Dec;7(12):1299-308. Epub 2011 Dec 1
Considerations for oral cholera vaccine use during outbreak after earthquake in Haiti, 2010-2011.
Date KA, Vicari A, Hyde TB, Mintz E, Danovaro-Holliday MC, Henry A, Tappero JW, Roels TH, Abrams J, Burkholder BT, Ruiz-Matus C, Andrus J, Dietz V.
Emerg Infect Dis. 2011 Nov;17(11):2105-12
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