Cholera

Indications: Vaccination provides protection against enteric disease, particularly diarrhoea, caused by ETEC or cholera.

Vaccination: vaccine is given as granulate, which is swallowed.

Protection: Vaccination gives protection against cholera and ETEC for 6 month, there after the protecting fades.

Side effects: does normally not occur.  

Cholera Vaccination Resource:

Burden of respiratory tract infections among paediatric in and out-patient units during 2010-11.
Mazumdar J, Chawla-Sarkar M, Rajendran K, Ganguly A, Sarkar UK, Ghosh S, Sarkar MD, Maulik S.
Eur Rev Med Pharmacol Sci. 2013 Mar;17(6):802-8
Algae-produced cholera toxin-Pfs25 fusion proteins as oral vaccines.
Gregory JA, Topol AB, Doerner DZ, Mayfield S.
Appl Environ Microbiol. 2013 Apr 19. [Epub ahead of print
The Minicommunity Design to Assess Indirect Effects of Vaccination.
Halloran ME.
Epidemiol Method. 2012 Aug 1;1(1):83-105
Immune responses to the O-specific polysaccharide antigen in children receiving a killed oral cholera vaccine compared to responses following natural cholera infection in Bangladesh.
Leung DT, Uddin T, Xu P, Aktar A, Johnson RA, Rahman MA, Alam MM, Bufano MK, Eckhoff G, Wu-Freeman Y, Yu Y, Sultana T, Khanam F, Saha A, Chowdhury F, Khan AI, Charles RC, Larocque RC, Harris JB, Calderwood SB, Kovác P, Qadri F, Ryan ET.
Clin Vaccine Immunol. 2013 Mar 20. [Epub ahead of print
Knowledge of, attitudes toward, and preventive practices relating to cholera and oral cholera vaccine among urban high-risk groups: findings of a cross-sectional study in Dhaka, Bangladesh.
Wahed T, Kaukab SS, Saha NC, Khan IA, Khanam F, Chowdhury F, Saha A, Khan AI, Siddik AU, Cravioto A, Qadri F, Uddin J.
BMC Public Health. 2013 Mar 19;13:242. doi: 10.1186/1471-2458-13-242
Rapid and scalable plant-based production of a cholera toxin B subunit variant to aid in mass vaccination against cholera outbreaks.
Hamorsky KT, Kouokam JC, Bennett LJ, Baldauf KJ, Kajiura H, Fujiyama K, Matoba N.
PLoS Negl Trop Dis. 2013 Mar;7(3):e2046. doi: 10.1371/journal.pntd.0002046. Epub 2013 Mar 7
Modelling typhoid risk in Dhaka Metropolitan Area of Bangladesh: the role of socio-economic and environmental factors.
Corner RJ, Dewan AM, Hashizume M.
Int J Health Geogr. 2013 Mar 16;12:13. doi: 10.1186/1476-072X-12-13
Prevention of fecal-orally transmitted diseases in travelers through an oral anticholeric vaccine (WC/rBS).
Gabutti G, Aquilina M, Cova M, Giuffrida S, Lizioli A, Protano D, Scrivano F, Tomasi A, Cucchi A, Cavallaro A; Collaborative Group for the Study of Fecal-Orally Transmitted Diseases in Travelers.
J Prev Med Hyg. 2012 Dec;53(4):199-203
Sublingual administration of bacteria-expressed influenza virus hemagglutinin 1 (HA1) induces protection against infection with 2009 pandemic H1N1 influenza virus.
Shim BS, Choi JA, Song HH, Park SM, Cheon IS, Jang JE, Woo SJ, Cho CH, Song MS, Kim H, Song KJ, Lee JM, Kim SW, Song DS, Choi YK, Kim JO, Nguyen HH, Kim DW, Bahk YY, Yun CH, Song MK.
J Microbiol. 2013 Feb;51(1):130-5. doi: 10.1007/s12275-013-2399-z. Epub 2013 Mar 2
[Mass vaccination against cholera].
Rokstad IS.
Tidsskr Nor Laegeforen. 2013 Jan 8;133(1):24. Norwegian. No abstract available.
A brief history of vaccines: smallpox to the present.
Hsu JL.
S D Med. 2013;Spec no:33-7
A Double Mutant Heat-Labile Toxin from Escherichia coli, LT(R192G/L211A), Is an Effective Mucosal Adjuvant for Vaccination against Helicobacter pylori Infection.
Sjökvist Ottsjö L, Flach CF, Clements J, Holmgren J, Raghavan S.
Infect Immun. 2013 May;81(5):1532-40. doi: 10.1128/IAI.01407-12. Epub 2013 Feb 25
Spontaneous development of IgM anti-cocaine antibodies in habitual cocaine users: effect on IgG antibody responses to a cocaine cholera toxin B conjugate vaccine.
Orson FM, Rossen RD, Shen X, Lopez AY, Wu Y, Kosten TR.
Am J Addict. 2013 Mar-Apr;22(2):169-74. doi: 10.1111/j.1521-0391.2013.00314.x. Epub 2013 Feb 1
Immunogenicity and protective efficacy of a dual subunit vaccine against respiratory syncytial virus and influenza virus.
Park MH, Chang J.
Immune Netw. 2012 Dec;12(6):261-8. doi: 10.4110/in.2012.12.6.261. Epub 2012 Dec 31
Local perceptions of cholera and anticipated vaccine acceptance in Katanga province, Democratic Republic of Congo.
Merten S, Schaetti C, Manianga C, Lapika B, Chaignat CL, Hutubessy R, Weiss MG.
BMC Public Health. 2013 Jan 22;13:60. doi: 10.1186/1471-2458-13-60
Effectiveness of the WC/rBS oral cholera vaccine in the prevention of traveler's diarrhea: A prospective cohort study.
López-Gigosos R, Campins M, Calvo MJ, Pérez-Hoyos S, Díez-Domingo J, Salleras L, Azuara MT, Martínez X, Bayas JM, Ramón Torrell JM, Pérez-Cobaleda MA, Núñez-Torrón ME, Gorgojo L, García-Rodríguez M, Díez-Díaz R, Armadans L, Sánchez-Fernández C, Mejías T, Masuet C, Pinilla R, Antón N, Segarra P.
Hum Vaccin Immunother. 2013 Jan 16;9(3). [Epub ahead of print
Cholera in Haiti: reproductive numbers and vaccination coverage estimates.
Mukandavire Z, Smith DL, Morris JG Jr.
Sci Rep. 2013;3:997. doi: 10.1038/srep00997. Epub 2013 Jan 10
Trial watch: Peptide vaccines in cancer therapy.
Vacchelli E, Martins I, Eggermont A, Fridman WH, Galon J, Sautès-Fridman C, Tartour E, Zitvogel L, Kroemer G, Galluzzi L.
Oncoimmunology. 2012 Dec 1;1(9):1557-1576
Genomic correlates of variability in immune response to an oral cholera vaccine.
Majumder PP, Sarkar-Roy N, Staats H, Ramamurthy T, Maiti S, Chowdhury G, Whisnant CC, Narayanasamy K, Wagener DK.
Eur J Hum Genet. 2012 Dec 19. doi: 10.1038/ejhg.2012.278. [Epub ahead of print
Vaccine specific immune response to an inactivated oral cholera vaccine and EPI vaccines in a high and low arsenic area in Bangladeshi children.
Saha A, Chowdhury MI, Nazim M, Alam MM, Ahmed T, Hossain MB, Hore SK, Sultana GN, Svennerholm AM, Qadri F.
Vaccine. 2013 Jan 11;31(4):647-52. doi: 10.1016/j.vaccine.2012.11.049. Epub 2012 Nov 28
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