Most cases of inflammatory bowel disease (IBD) can be correctly labelled as Crohn's disease (CD) or ulcerative colitis (UC) with careful initial gross and microscopic examination of biopsy and resection specimens togeTher with close clinical and radiological correlation. Until we understand more of the aetiology and immunology of IBD we should admit that there are limitations imposed by current diagnostic criteria, consider the use of reporting proforma to improve diagnostic accuracy, and accept that in a small number of patients clinicopathological features will overlap, and CD may masquerade as UC.
Related ArticlesDifferentiating ulcerative colitis from Crohn disease in children and young adults: report of a working group of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the Crohn's and Colitis Foundation of America.J Pediatr Gastroenterol Nutr. 2007
Differentiating ulcerative colitis from Crohn disease in children and young adults: report of a working group of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the Crohn's and Colitis Foundation of America.
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Matsui T, Yao T, Sakurai T, Yao K, Hirai F, Matake H, Tsuda S, Wada Y, Iwashita A, Kamachi S. J Gastroenterol. 2003; 38(7):647-55.
Review Crohn's disease, ulcerative colitis or indeterminate colitis--how important is it to differentiate?Acta Gastroenterol Belg. 2001
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Differential effects of energy balance on experimentally-induced colitis.World J Gastroenterol. 2012
Differential effects of energy balance on experimentally-induced colitis.
McCaskey SJ, Rondini EA, Langohr IM, Fenton JI. World J Gastroenterol. 2012 Feb 21; 18(7):627-36.
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