Authors:
Address: Intensive Care Department, Brugmann University Hospital, 4 Place Van Gehuchten, 1020, Brussels, Belgium. david.debels@chu-brugmann.be.
Journal:

Publication:
Free Text: Successful treatment of Chlamydophila pneumoniae acute respiratory distress syndrome with extracorporeal membrane oxygenator: a case report and diagnostic review.

abstract

ABSTRACT:

INTRODUCTION:

Chlamydophila pneumoniae is a respiratory pathogen known to infect the upper and lower respiratory tracts. Infection severity can range from sub-clinical pulmonary infection to acute respiratory distress syndrome.

case PRESENTATION:

A previously healthy 62-year-old Caucasian man was admitted to our hospital for acute respiratory failure. Serum samples obtained every week starting from the day of admission showed clear-cut seroconversion for C. pneumoniae antibodies. All other cultures obtained during the first days of hospitalization were negative. Despite maximal ventilatory support (high positive end expiratory pressure, fraction of inspired oxygen of 1.0, nitric oxide inhalation, neuromuscular blocking agents and prone positioning), our patient remained severely hypoxemic, which led us to initiate an extracorporeal membrane oxygenation treatment. Extracorporeal membrane oxygenation and hemodiafiltration were withdrawn on day 12. Our patient was extubated on day 18 and discharged from our Intensive Care Unit on day 20. He went home a month later.

CONCLUSION:

We describe the first published case of acute respiratory distress syndrome due to C. pneumoniae infection Successfully treated by extracorporeal membrane oxygenation, a very useful tool in this syndrome. A quick and specific method for the definite diagnosis of Chlamydophila infection should be developed.

Related Articles
Extracorporeal membrane oxygenation as a bridge to liver transplantation for acute respiratory distress syndrome-induced life-threatening hypoxaemia aggravated by hepatopulmonary syndrome.
Crit Care. 2011
Extracorporeal membrane oxygenation as a bridge to liver transplantation for acute respiratory distress syndrome-induced life-threatening hypoxaemia aggravated by hepatopulmonary syndrome.
Monsel A, Mal H, Brisson H, Luo R, Eyraud D, Vézinet C, Do CH, Lu Q, Vaillant JC, Hannoun L, et al. Crit Care. 2011; 15(5):R234. Epub 2011 Sep 29.
[Recommendations of the Infectious Diseases Work Group (GTEI) of the Spanish Society of Intensive and Critical Care Medicine and Coronary Units (SEMICYUC) and the Infections in Critically Ill Patients Study Group (GEIPC) of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) for the diagnosis and treatment of influenza A/H1N1 in seriously ill adults admitted to the Intensive Care Unit].
Med Intensiva. 2012
[Recommendations of the Infectious Diseases Work Group (GTEI) of the Spanish Society of Intensive and Critical Care Medicine and Coronary Units (SEMICYUC) and the Infections in Critically Ill Patients Study Group (GEIPC) of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) for the diagnosis and treatment of influenza A/H1N1 in seriously ill adults admitted to the Intensive Care Unit].
Rodríguez A, Alvarez-Rocha L, Sirvent JM, Zaragoza R, Nieto M, Arenzana A, Luque P, Socías L, Martín M, Navarro D, et al. Med Intensiva. 2012 Mar; 36(2):103-37. Epub 2012 Jan 13.
Controlled airway pressure therapy, nitric oxide inhalation, prone position, and extracorporeal membrane oxygenation (ECMO) as components of an integrated approach to ARDS.
Anesthesiology. 1999
Controlled airway pressure therapy, nitric oxide inhalation, prone position, and extracorporeal membrane oxygenation (ECMO) as components of an integrated approach to ARDS.
Ullrich R, Lorber C, Röder G, Urak G, Faryniak B, Sladen RN, Germann P. Anesthesiology. 1999 Dec; 91(6):1577-86.
Review Extracorporeal support in an adult with severe carbon monoxide poisoning and shock following smoke inhalation: a case report.
Perfusion. 2000
Review Extracorporeal support in an adult with severe carbon monoxide poisoning and shock following smoke inhalation: a case report.
McCunn M, Reynolds HN, Cottingham CA, Scalea TM, Habashi NM. Perfusion. 2000 Mar; 15(2):169-73.
Review Extracorporeal membrane oxygenation for ARDS in adults.
N Engl J Med. 2011
Review Extracorporeal membrane oxygenation for ARDS in adults.
Brodie D, Bacchetta M. N Engl J Med. 2011 Nov 17; 365(20):1905-14.

To top • Home

---

Show map | Diseases | Vaccination | Chronic disease | Medicine | Pregnancy | Heat & Sunburn | Cold | Security | Useful tips | Faq | News

TraveldoctorOnline 2001 • Disclaimer • webmaster