Authors:
Address: Pediatric Infection Research Center, Mofid Children Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Journal:

Publication:
Free Text: Study Prevalence of Verotoxigenic E.coli Isolated from Urinary Tract Infections (UTIs) in an Iranian Children Hospital.

abstract

BACKGROUND AND OBJECTIVES:

Urinary Tract Infections (UTI) caused by enterohemorrhagic Escherichia coli (EHEC) is one of the most important diseases in infants and Children. If there would not be any useful diagnosis and treatment it may be resulted in diseases such as acute renal failure, thrombocytopenia and hemolytic anemia. The aim of this Study was to determine frequency of Verotoxigenic E.coli isolates in urine of children with (UTIs) in Mofid children Hospital.

METHODS:

During one year from September 2008 to august 2009, urine specimens were taken from children who suspected to UTI admitted to Mofid Children Hospital. E.coli strains that indicated beta hemolytic on sheep blood agar, negative sorbitol fermentation on SMAC (sorbitol macconky agar) and negative motility on SIM were tested by PCR and serologic (VITEC-RPLA kit) methods for detecting toxin genes and production of toxin, respectively.

RESULTS:

Among 12572 urine specimens were taken from children admitted to Mofid hospital, we Isolated 378 E.coli from urine samples which only 9 isolates were EHEC. Only five EHEC strains (55%) which produced vtx genes, were detected by serologic and PCR methods.

CONCLUSION:

The Prevalence of urinary infections caused by EHEC strains is very significant because it causes aggravating pathologic effects. Thus we suggest rapid method for identification of this bacteria and proper treatment to Inhibition of unwanted complications.

Related Articles
Review Bacterial characteristics of importance for recurrent urinary tract infections caused by Escherichia coli.
Dan Med Bull. 2011
Review Bacterial characteristics of importance for recurrent urinary tract infections caused by Escherichia coli.
Ejrnæs K. Dan Med Bull. 2011 Apr; 58(4):B4187.
Risk factors for ciprofloxacin resistance among Escherichia coli strains isolated from community-acquired urinary tract infections in Turkey.
J Antimicrob Chemother. 2005
Risk factors for ciprofloxacin resistance among Escherichia coli strains isolated from community-acquired urinary tract infections in Turkey.
Arslan H, Azap OK, Ergönül O, Timurkaynak F, Urinary Tract Infection Study Group. J Antimicrob Chemother. 2005 Nov; 56(5):914-8. Epub 2005 Sep 20.
Etiology and antibiotic resistance patterns of community-acquired urinary tract infections in J N M C Hospital Aligarh, India.
Ann Clin Microbiol Antimicrob....
Etiology and antibiotic resistance patterns of community-acquired urinary tract infections in J N M C Hospital Aligarh, India.
Akram M, Shahid M, Khan AU. Ann Clin Microbiol Antimicrob. 2007 Mar 23; 6:4. Epub 2007 Mar 23.
Comparison of Escherichia coli uropathogenic genes (kps, usp and ireA) and enteroaggregative genes (aggR and aap) via multiplex polymerase chain reaction from suprapubic urine specimens of young children with fever.
Scand J Urol Nephrol. 2009
Comparison of Escherichia coli uropathogenic genes (kps, usp and ireA) and enteroaggregative genes (aggR and aap) via multiplex polymerase chain reaction from suprapubic urine specimens of young children with fever.
Park HK, Jung YJ, Chae HC, Shin YJ, Woo SY, Park HS, Lee SJ. Scand J Urol Nephrol. 2009; 43(1):51-7.
Review Urinary tract infections in children younger than 5 years of age: epidemiology, diagnosis, treatment, outcomes and prevention.
Paediatr Drugs. 2001
Review Urinary tract infections in children younger than 5 years of age: epidemiology, diagnosis, treatment, outcomes and prevention.
Schlager TA. Paediatr Drugs. 2001; 3(3):219-27.

To top • Home

---

Show map | Diseases | Vaccination | Chronic disease | Medicine | Pregnancy | Heat & Sunburn | Cold | Security | Useful tips | Faq | News

TraveldoctorOnline 2001 • Disclaimer • webmaster