[Mini bronchoalveolar lavage in patients with severe respiratory failure].

Authors:
Address: Departamento de Medicina Intensiva, Departamento de Enfermedades Respiratorias, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile. andresen@med.puc.cl
Journal:


Publication:

abstract

BACKGROUND:

To recognize the etiological agent responsible for severe acute respiratory failure (ARF) in patients in mechanical ventilation (MV) is important to determine their treatment and prognosis, and to avoid the excessive use of antibiotics. Mini bronchoalveolar lavage (mini BAL) is a blind, non bronschoscopic procedure, used to obtain samples from the lower respiratory tract from patients on mechanical ventilation (MV).

AIM:

To assess the feasibility, complications and preliminary results of mini BAL among patients with severe ARF on MV.

MATERIAL AND METHODS:

Prospective study in 17 patients with acute lung injury (ALI ) or acute respiratory distess syndrome (ARDS) on MV and with negative conventional microbiological studies. Mini BAL was performed using standardized protocols. Hemodynamic and respiratory parameters where measured before and after the procedure. Samples obtained were sent to quantitative cultures.

RESULTS:

At baseline: APACHE II score of 22 ± 6,7, PaO2/FiO2 ratio was 176.6 ± 48.6 and the oxygenation index was 9.74 ± 3.78. All procedures were performed by an ICU resident. Thirty five percent of the procedures had positive cultures and no complications related to the procedures were reported. The procedure lasted an average of 12 minutes and the instilled and rescued volume were 60 ml and 19.6 ml, respectively. There were no significant differences between hemodynamic and respiratory variables before and after the procedure.

CONCLUSIONS:

Mini BAL is a safe, fast and easy technique for obtaining samples from the inferior airway in patients with ALI or ARDS on MV.



Related Articles
Inflammatory mediators in bronchoalveolar lavage fluid and plasma in leukocytopenic patients with septic shock-induced acute respiratory distress syndrome.
Crit Care Med. 1998
Inflammatory mediators in bronchoalveolar lavage fluid and plasma in leukocytopenic patients with septic shock-induced acute respiratory distress syndrome.
Kiehl MG, Ostermann H, Thomas M, Müller C, Cassens U, Kienast J. Crit Care Med. 1998 Jul; 26(7):1194-9.
Comparison of two non-bronchoscopic methods for evaluating inflammation in patients with acute hypoxaemic respiratory failure.
Crit Care. 2009
Comparison of two non-bronchoscopic methods for evaluating inflammation in patients with acute hypoxaemic respiratory failure.
Colucci G, Domenighetti G, Della Bruna R, Bonilla J, Limoni C, Matthay MA, Martin TR. Crit Care. 2009; 13(4):R134. Epub 2009 Aug 11.
Combined effects of prone positioning and airway pressure release ventilation on gas exchange in patients with acute lung injury.
Acta Anaesthesiol Scand. 2003
Combined effects of prone positioning and airway pressure release ventilation on gas exchange in patients with acute lung injury.
Varpula T, Jousela I, Niemi R, Takkunen O, Pettilä V. Acta Anaesthesiol Scand. 2003 May; 47(5):516-24.
Review Pathophysiology of prone positioning in the healthy lung and in ALI/ARDS.
Minerva Anestesiol. 2001
Review Pathophysiology of prone positioning in the healthy lung and in ALI/ARDS.
Pelosi P, Caironi P, Taccone P, Brazzi L. Minerva Anestesiol. 2001 Apr; 67(4):238-47.
Review Lung recruitment maneuvers in acute respiratory distress syndrome and facilitating resolution.
Crit Care Med. 2003
Review Lung recruitment maneuvers in acute respiratory distress syndrome and facilitating resolution.
Valente Barbas CS. Crit Care Med. 2003 Apr; 31(4 Suppl):S265-71.

To top Home


Show map | Diseases | Vaccination | Chronic disease | Medicine | Pregnancy | Heat & Sunburn | Cold | Security | Useful tips | Faq | News

TraveldoctorOnline 2001 • Disclaimer webmaster

The contents within traveldoctoronline are presented only for informational purposes and cannot substitute for professional health care or any other medical treatment.All users of this website with health problems should be oblige always to consult their medical doctor before starting any treatment.