[Melatonin in the system of neurohormonal regulation in man. Part 1].

Authors: Baksheev VI Kolomoets NM
Address:
Journal:

Publication:

abstract

Part I of this systematic review is devoted to the history of Melatonin (MT) studies, mechanisms of MT action, and its clinical importance as a universal modulator of physiological functions applicable to the treatment of numerous disorders, in the first place respiratory diseases. MT participates in regulation of arterial pressure and myocardial contractility, it increases antioxidative potential, plays an important role in regulation of circadian rhythms, sleep and adaptation to jet lag. Antioxidative, antitumorigenic, immunomodulatory, antidepressive, anti-anxiety, and hypnogenic activities of exogenous MT coupled to the absence of toxicity make it an attractive agent for the treatment of many human diseases especially in old age.

Related Articles
Review Effects of melatonin on vertebrate circadian systems.
Trends Neurosci. 1990
Review Effects of melatonin on vertebrate circadian systems.
Cassone VM. Trends Neurosci. 1990 Nov; 13(11):457-64.
Review Role of melatonin in the regulation of human circadian rhythms and sleep.
J Neuroendocrinol. 2003
Review Role of melatonin in the regulation of human circadian rhythms and sleep.
Cajochen C, Kräuchi K, Wirz-Justice A. J Neuroendocrinol. 2003 Apr; 15(4):432-7.
Review The role of melatonin in the neurodegenerative diseases.
Bratisl Lek Listy. 2005
Review The role of melatonin in the neurodegenerative diseases.
Olakowska E, Marcol W, Kotulska K, Lewin-Kowalik J. Bratisl Lek Listy. 2005; 106(4-5):171-4.
Review [The problems of the central regulation of immune system biorhythms: the role of exogenous and endogenous melatonin].
Vestn Ross Akad Med Nauk. 2006
Review [The problems of the central regulation of immune system biorhythms: the role of exogenous and endogenous melatonin].
Trufakin VA, Shurlygina AV. Vestn Ross Akad Med Nauk. 2006; (9-10):121-7.
Review [Melatonin: its role in the system of neurohumoral regulation in man. Part 2].
Klin Med (Mosk). 2011
Review [Melatonin: its role in the system of neurohumoral regulation in man. Part 2].
Baksheev VI, Kolomoets NM. Klin Med (Mosk). 2011; 89(2):8-13.

To top • Home

TraveldoctorOnline 2001 • Disclaimer • webmaster

The contents within traveldoctoronline are presented only for informational purposes and cannot substitute for professional health care or any other medical treatment.All users of this website with health problems should be oblige always to consult their medical doctor before starting any treatment.