Medicine

Quinine

Indications: This medicine is an antimalarial agent used to treat malaria. It may also be used to treat nocturnal leg cramps and other conditions as determined by your doctor.

Directions for use: 10 mg /kg body weight three times the day in 7 ?10 days.

Pregnancy: May cause abortion.

Side effects: include diarrhoea, nausea, stomach cramps, or dizziness. If they continue or are bothersome, check with your doctor. CHECK WITH YOUR DOCTOR AS SOON AS POSSIBLE if you experience blurred vision, ringing in the ears, flushing, rash, sore throat or fever, vomiting, loss of appetite, weight loss, sudden onset of cold sweat, fatigue, shakiness, fast heartbeat, vision changes, confusion, personality changes, or difficulty breathing. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist.

Quinine Resource:

Enantioselective Synthesis of Quaternary α-Aminophosphonates via Conjugate Addition of α-Nitrophosphonates to Enones (§).
Bera K, Namboothiri IN.
Org Lett. 2012 Feb 8. [Epub ahead of print
Medicinal plants used by various tribes of bangladesh for treatment of malaria.
Rahmatullah M, Hossan S, Khatun A, Seraj S, Jahan R.
Malar Res Treat. 2012;2012:371798. Epub 2012 Jan 23
Pattern of the Antimalarials Prescription during Pregnancy in Bangui, Central African Republic.
Manirakiza A, Soula G, Laganier R, Klement E, Djallé D, Methode M, Madji N, Heredeïbona LS, Le Faou A, Delmont J.
Malar Res Treat. 2011;2011:414510. Epub 2011 Jul 15
Mangiferin exerts hepatoprotective activity against d-galactosamine induced acute toxicity and oxidative/nitrosative stress via Nrf2-NFκB pathways.
Das J, Ghosh J, Roy A, Sil PC.
Toxicol Appl Pharmacol. 2012 Jan 30. [Epub ahead of print
Optimization of the production of gurmarin, a sweet-taste-suppressing protein, secreted by the methylotrophic yeast Pichia pastoris.
Sigoillot M, Brockhoff A, Lescop E, Poirier N, Meyerhof W, Briand L.
Appl Microbiol Biotechnol. 2012 Feb 4. [Epub ahead of print
Parental administration of unprescribed antimalarial drugs to treat febrile children in Gabon.
Mawili-Mboumba DP, Bouyou-Akotet MK, Kombila M.
Sante. 2011 Jul 1;21(3):127-131
Preference for Sucralose Predicts Behavioral Responses to Sweet and Bittersweet Tastants.
Loney GC, Torregrossa AM, Carballo C, Eckel LA.
Chem Senses. 2012 Jan 25. [Epub ahead of print
Iron(III) Protoporphyrin IX Complexes of the Antimalarial Cinchona Alkaloids Quinine and Quinidine.
de Villiers KA, Gildenhuys J, le Roex T.
ACS Chem Biol. 2012 Feb 3. [Epub ahead of print
Production and radioprotective effects of pyrroloquinoline quinone.
Xiong XH, Zhao Y, Ge X, Yuan SJ, Wang JH, Zhi JJ, Yang YX, Du BH, Guo WJ, Wang SS, Yang DX, Zhang WC.
Int J Mol Sci. 2011;12(12):8913-23. Epub 2011 Dec 5
Rheinheimera longhuensis sp. nov., isolated from a slightly alkaline lake in northeast of China and emended description of genus Rheinheimera Brettar et al. 2002 emend. Merchant et al. 2007 emend. Chen et al. emend. Li et al. 2011.
Liu Y, Jiang JT, Xu CJ, Liu YH, Song XF, Li H, Liu ZP.
Int J Syst Evol Microbiol. 2012 Jan 20. [Epub ahead of print
Apo-8'-lycopenal Induces Expression of HO-1 and NQO-1 via the ERK/p38-Nrf2-ARE Pathway in Human HepG2 Cells.
Yang CM, Huang SM, Liu CL, Hu ML.
J Agric Food Chem. 2012 Feb 1. [Epub ahead of print
Effect of quinine therapy on plasma glucose and plasma insulin levels in pregnant women infected with Plasmodium falciparum malaria in Gezira state.
Elbadawi NE, Mohamed MI, Dawod OY, Ali KE, Daoud OH, Ali EM, Ahmed EG, Mohamed AE.
East Mediterr Health J. 2011 Sep;17(9):697-700
Non-drug therapies for lower limb muscle cramps.
Blyton F, Chuter V, Walter KE, Burns J.
Cochrane Database Syst Rev. 2012 Jan 18;1:CD008496
Multiple Processes Underlie Benzodiazepine-Mediated Increases in the Consumption of Accepted and Avoided Stimuli.
Pittman DW, McGinnis MR, Richardson LM, Miller EJ, Alimohamed ML, Baird JP.
Chem Senses. 2012 Jan 16. [Epub ahead of print
Natural and synthetic modulators of SK (K(ca)2) potassium channels inhibit magnesium-dependent activity of the kinase-coupled cation channel TRPM7.
Chubanov V, Mederos Y Schnitzler M, Meißner M, Schäfer S, Abstiens K, Hofmann T, Gudermann T.
Br J Pharmacol. 2012 Jan 13. doi: 10.1111/j.1476-5381.2012.01855.x. [Epub ahead of print
[Unsuspected danger of a medicinal preparation].
Gohy S, Quennery S, Pieters T, Weynand B, Liistro G.
Rev Mal Respir. 2012 Jan;29(1):94-7. Epub 2011 Dec 14. French.
Atorvastatin treatment is effective when used in combination with mefloquine in an experimental cerebral malaria murine model.
Souraud JB, Briolant S, Dormoi J, Mosnier J, Savini H, Baret E, Amalvict R, Soulard R, Rogier C, Pradines B.
Malar J. 2012 Jan 10;11(1):13. [Epub ahead of print
Malaria Survey in Post-Earthquake Haiti--2010.
Townes D, Existe A, Boncy J, Magloire R, Vely JF, Amsalu R, Tavernier MD, Muigai J, Hoibak S, Albert M, McMorrow M, Slutsker L, Kachur SP, Chang M.
Am J Trop Med Hyg. 2012 Jan;86(1):29-31
Discordant temporal evolution of Pfcrt and Pfmdr1 genotypes and Plasmodium falciparum in vitro drug susceptibility to 4-aminoquinolines after changing drug policy in French Guiana.
Legrand E, Yrinesi J, Ekala MT, Péneau J, Volney B, Berger F, Bouchier C, Bertani S, Musset L, Meynard JB, Mercereau-Puijalon O.
Antimicrob Agents Chemother. 2012 Jan 9. [Epub ahead of print
Dichlorvos and lindane induced oxidative stress in rat brain: Protective effects of ginger.
Sharma P, Singh R.
Pharmacognosy Res. 2012 Jan;4(1):27-32
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