Medicine

Quinine

Indications: This medicine is an antimalarial agent used to treat malaria. It may also be used to treat nocturnal leg cramps and other conditions as determined by your doctor.

Directions for use: 10 mg /kg body weight three times the day in 7 ?10 days.

Pregnancy: May cause abortion.

Side effects: include diarrhoea, nausea, stomach cramps, or dizziness. If they continue or are bothersome, check with your doctor. CHECK WITH YOUR DOCTOR AS SOON AS POSSIBLE if you experience blurred vision, ringing in the ears, flushing, rash, sore throat or fever, vomiting, loss of appetite, weight loss, sudden onset of cold sweat, fatigue, shakiness, fast heartbeat, vision changes, confusion, personality changes, or difficulty breathing. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist.

Quinine Resource:

Short-course treatment of vulvovaginal candidiasis: comparative study of fluconazole and intra-vaginal fenticonazole.
Murina F, Graziottin A, Felice R, Di Francesco S, Mantegazza V.
Minerva Ginecol. 2012 Apr;64(2):89-94
Diffuse mucocutaneous leishmaniasis.
Mathur A, Mathur S, Agarwal H, Kulshresth M, Joshi K, Dubey T, Butoli J.
J Assoc Physicians India. 2011 Oct;59:653. No abstract available.
Risk factors and outcomes of candidemia caused by biofilm-forming isolates in a tertiary care hospital.
Tumbarello M, Fiori B, Trecarichi EM, Posteraro P, Losito AR, De Luca A, Sanguinetti M, Fadda G, Cauda R, Posteraro B.
PLoS One. 2012;7(3):e33705. Epub 2012 Mar 30
[Study on in vitro susceptibility of Candida spp. isolated from blood culture].
Grandesso S, Sapino B, Mazzuccato S, Solinas M, Bedin M, D'Angelo M, Gion M.
Infez Med. 2012 Mar;20(1):25-30. Italian.
Use of Terbinafine in the Treatment Protocol of Intestinal Cryptococcus neoformans in a Dog.
Olsen GL, Deitz KL, Flaherty HA, Lockhart SR, Hurst SF, Haynes JS.
J Am Anim Hosp Assoc. 2012 May;48(3):216-20. Epub 2012 Apr 3
In vitro evaluation of Malassezia pachydermatis susceptibility to azole compounds using E-test and CLSI microdilution methods.
Cafarchia C, Figueredo LA, Iatta R, Colao V, Montagna MT, Otranto D.
Med Mycol. 2012 Apr 3. [Epub ahead of print
Cost-effectiveness of posaconazole versus fluconazole or itraconazole in the prevention of invasive fungal infections among high-risk neutropenic patients in Spain.
Grau S, de la Cámara R, Sabater FJ, Jarque I, Carreras E, Casado MA, Sanz MA.
BMC Infect Dis. 2012 Apr 3;12(1):83
Beauveria bassiana keratitis in bullous keratopathy: antifungal sensitivity testing and management.
Figueira L, Pinheiro D, Moreira R, Pinto E, Simões J, Camisa E, Torrão L, Palmares J, Falcão-Reis F.
Eur J Ophthalmol. 2012 Mar 27:0. doi: 10.5301/ejo.5000152. [Epub ahead of print
[Trends in systemic antifungal use in critically ill patients. Multicenter observational study, 2006-2010.]
Olaechea-Astigarraga PM, Alvarez-Lerma F, Palomar-Martínez M, Insausti-Ordeñana J, López-Pueyo MJ, Seijas-Betolaza I, Otal-Entraigas JJ, Gimeno-Costa R, Gracia-Arnillas MP; Grupo ENVIN-HELICS.
Enferm Infecc Microbiol Clin. 2012 Mar 28. [Epub ahead of print] Spanish.
[Invasive candidiasis in a lung retransplantation recipient].
de Merlo-Martínez P, Iranzo-Valero R, García-Fernández J.
Rev Iberoam Micol. 2012 Apr;29(2):97-101. Spanish.
[Echinocandins in a critically ill patient during continuous venovenous renal replacement].
Aguilar G, Carbonell JA, Ferrando C, Badenes R, Belda FJ.
Rev Iberoam Micol. 2012 Apr;29(2):85-9. Spanish.
[Candida peritonitis in a haemodynamically stable patient. First choice of antifungal treatment … fluconazole?].
Maseda E, Gilsanz F.
Rev Iberoam Micol. 2012 Apr;29(2):81-4. Spanish.
Potent Antifungal Activity of Pure Compounds from Traditional Chinese Medicine Extracts against Six Oral Candida Species and the Synergy with Fluconazole against Azole-Resistant Candida albicans.
Yan Z, Hua H, Xu Y, Samaranayake LP.
Evid Based Complement Alternat Med. 2012;2012:106583. Epub 2012 Feb 12
Invasive aspergillosis: a severe infection in juvenile systemic lupus erythematosus patients.
Silva MF, Ribeiro AS, Fiorot FJ, Aikawa NE, Lotito AP, Campos LM, Mauad T, Silva CA.
Lupus. 2012 Mar 26. [Epub ahead of print
Safety and tolerability of voriconazole in patients with baseline renal insufficiency and candidemia.
Oude Lashof AM, Sobel JD, Ruhnke M, Pappas PG, Viscoli C, Schlamm HT, Rex JH, Kullberg BJ.
Antimicrob Agents Chemother. 2012 Jun;56(6):3133-7. Epub 2012 Mar 26
Efficacy of micafungin in empirical therapy of deep mycosis in surgically ill patients.
Okamoto K, Katsuki T, Tamura T, Kanemitsu S, Minagawa N, Torigoe T, Shibao K, Higure A, Yamaguchi K.
J Infect Chemother. 2012 Mar 27. [Epub ahead of print
Neonatal invasive candidiasis in Tunisian hospital: incidence, risk factors, distribution of species and antifungal susceptibility.
Ben Abdeljelil J, Saghrouni F, Nouri S, Geith S, Khammari I, Fathallah A, Sboui H, Ben Saïd M.
Mycoses. 2012 Mar 26. doi: 10.1111/j.1439-0507.2012.02189.x. [Epub ahead of print
Extensive Genetic Diversity within the Dutch Clinical Cryptococcus neoformans Population.
Hagen F, Illnait-Zaragozí MT, Meis JF, Chew WH, Curfs-Breuker I, Mouton JW, Hoepelman AI, Spanjaard L, Verweij PE, Kampinga GA, Kuijper EJ, Boekhout T, Klaassen CH.
J Clin Microbiol. 2012 Jun;50(6):1918-26. Epub 2012 Mar 21
New triazole derivatives as antifungal agents: synthesis via click reaction, in vitro evaluation and molecular docking studies.
Zou Y, Zhao Q, Liao J, Hu H, Yu S, Chai X, Xu M, Wu Q.
Bioorg Med Chem Lett. 2012 Apr 15;22(8):2959-62. Epub 2012 Feb 23
Cryptococcal osteomyelitis of the scapula and rib in an immunocompetent patient.
Zhang Y, Yu YS, Tang ZH, Zang GQ.
Med Mycol. 2012 Mar 21. [Epub ahead of print
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