Infectious etiologies of acute febrile illness among patients seeking health care in south-central Cambodia.
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Infectious etiologies of acute febrile illness among patients seeking health care in south-central Cambodia.
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Authors:
Address: United States Naval Medical Research Unit 2, Jakarta, Indonesia. matthew.kasper@med.navy.mil
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Publication:
Free Text: Infectious etiologies of acute febrile illness among patients seeking health care in south-central Cambodia.
The agents of human febrile illness can vary by region and country suggesting that diagnosis, treatment, and control programs need to be based on a methodical evaluation of area-specific etiologies. From December 2006 to December 2009, 9,997 individuals presenting with acute febrile illness at nine health care clinics in south-central Cambodia were enrolled in a study to elucidate the etiologies. Upon enrollment, respiratory specimens, whole blood, and serum were collected. Testing was performed for viral, bacterial, and parasitic pathogens. Etiologies were identified in 38.0% of patients. Influenza was the most frequent pathogen, followed by dengue, malaria, and bacterial pathogens isolated from blood culture. In addition, 3.5% of enrolled patients were infected with more than one pathogen. Our data provide the first systematic assessment of the etiologies of acute febrile illness in south-central Cambodia. Data from syndromic-based surveillance studies can help guide public health responses in developing nations.
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