Human clinical isolates of Corynebacterium diphtheriae and Corynebacterium ulcerans collected in Canada from 1999 to 2003 but not fitting reporting criteria for cases of diphtheria.

Authors: Dewinter LM,Bernard KA,Romney MG,
Address: National Microbiology Laboratory, Public Health Agency of Canada, 1015 Arlington St., Winnipeg, Manitoba, Canada R3E 3R2. leanne_dewinter@phac-aspc.gc.ca
Journal: J Clin Microbiol.

Publication: 2005 Jul;43(7):3447-9.

abstract

A 5-year collection of Corynebacterium diphtheriae and Corynebacterium ulcerans Human clinical isolates yielded nine isolates from blood cultures of patients with invasive infections, stressing the importance of C. diphtheriae as a serious blood-borne pathogen. Seven percent of C. diphtheriae and 100% of C. ulcerans isolates produced diphtheria toxin, demonstrating that toxigenic corynebacteria continue to circulate.

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