New formulations have been designed to increase The efficacy and bioavailability of the oral drugs mebendazole and nocodazole and were tested in CBA mice. A considerable increase in efficacy was established for a solid disperse formulation of certain composition with a relatively lower toxicity than in aqueous suspensions of the drugs.
Related Articles[Experimental chemotherapy of alveococcosis. 9. The pharmacokinetics and effectiveness of mebendazole when administered by peroral and intramuscular routes to infected mice].Med Parazitol (Mosk). 1986
[Experimental chemotherapy of alveococcosis. 9. The pharmacokinetics and effectiveness of mebendazole when administered by peroral and intramuscular routes to infected mice].
Dzhabarova VI, Lur'e AA, Krotov AI. Med Parazitol (Mosk). 1986 Sep-Oct; (5):63-7.
[Effect of phospholipids on mebendazole pharmacokinetics in experimental multilocular echinococcosis].Med Parazitol (Mosk). 1986
[Effect of phospholipids on mebendazole pharmacokinetics in experimental multilocular echinococcosis].
Lur'e AA, Dzhabarova VI, Krotov AI, Shcherbakov AM. Med Parazitol (Mosk). 1986 Sep-Oct; (5):67-71.
[Experimental study of the chemotherapy of echinococcosis using intramuscular injections of a mebendazole suspension].Med Parazitol (Mosk). 1983
[Experimental study of the chemotherapy of echinococcosis using intramuscular injections of a mebendazole suspension].
Krotov AI, Dzhabarova VI, Pereverzeva EV, Lopatin BV, Dobrotvorskiĭ AE. Med Parazitol (Mosk). 1983 Sep-Oct; (5):61-3.
Review [Research progress on the efficacy, metabolism and bioavailability of mebendazole in hydatid disease].Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Cho...
Review [Research progress on the efficacy, metabolism and bioavailability of mebendazole in hydatid disease].
Liu CS, Zhang HB. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2009 Dec; 27(6):513-9.
Review [Chemotherapy alone or as adjuvant treatment to surgery for alveolar and cystic echinococcosis].Chirurg. 2000
Review [Chemotherapy alone or as adjuvant treatment to surgery for alveolar and cystic echinococcosis].
Ammann RW. Chirurg. 2000 Jan; 71(1):9-15.
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