Yellow Fever
Yellow fever is a viral disease, which is spread by the bite of a mosquito. The geographical distribution of yellow fever is confined to Equatorial Africa and South America . Strangely yellow fever is unknown in Asia despite the presence of mosquitoes capable of spreading the virus.
Nevertheless in general, all travellers going to an endemic area require a yellow fever vaccination certificate and travellers going to some parts of Asia from an endemic region will also require a certificate.Please refr to list of countries .
Manifestation: The disease can have three different presentations:
Subclinical, without any symptoms. 2. Flu-like disease with:
Fever Muscle pain Head-ache Nausea Vomiting Recovery Severe fever with death in a few days with kidney failure, liver failure and haemorrhage. Diagnose and treatment : No curative treatment is available. Overall about 5% of patients die. Those who recover do so completely and are immune thereafter.
Vaccination : Vaccine against yellow fever is available and effective. This vaccine is recommended before travelling to several countries.
Prevent yellow fever by :
Vaccination Avoid mosquito bites by remaining in well screened areas Avoid mosquito bites by remaining in air-conditioned areas. Use mosquito repellents on skin and clothing Bring aerosol insecticides to use indoors Use bednets
Yellow Fever Resource: The other Dr Hooker: William Dawson Hooker (1816-40). Lambert H.J Med Biogr . 2011 Nov;19(4):141-4Spatial and temporal abundance of three sylvatic yellow fever vectors in the influence area of the Manso hydroelectric power plant, Mato Grosso, Brazil. Ribeiro AL, Miyazaki RD, Silva M, Zeilhofer P.J Med Entomol . 2012 Jan;49(1):223-6Genetic Mapping a Meiotic Driver That Causes Sex Ratio Distortion in the Mosquito Aedes aegypti. Shin D, Mori A, Severson DW.J Hered . 2012 Feb 3. [Epub ahead of printThe Safety of Yellow Fever Vaccine 17D or 17DD in Children, Pregnant Women, HIV+ Individuals, and Older Persons: Systematic Review. Thomas RE, Lorenzetti DL, Spragins W, Jackson D, Williamson T.Am J Trop Med Hyg . 2012 Feb;86(2):359-72Assessing the risk of international spread of yellow Fever virus: a mathematical analysis of an urban outbreak in asuncion, 2008. Johansson MA, Arana-Vizcarrondo N, Biggerstaff BJ, Gallagher N, Marano N, Staples JE.Am J Trop Med Hyg . 2012 Feb;86(2):349-58A "Genome-to-Lead" Approach for Insecticide Discovery: Pharmacological Characterization and Screening of Aedes aegypti D(1)-like Dopamine Receptors. Meyer JM, Ejendal KF, Avramova LV, Garland-Kuntz EE, Giraldo-Calderón GI, Brust TF, Watts VJ, Hill CA.PLoS Negl Trop Dis . 2012 Jan;6(1):e1478. Epub 2012 Jan 24[Travellers to South america]. Lloveras SC.Rev Chilena Infectol . 2011 Dec;28(6):520-8. Epub 2012 Jan 5. Spanish.Vaccination against infection in patients with multiple sclerosis. Loebermann M, Winkelmann A, Hartung HP, Hengel H, Reisinger EC, Zettl UK.Nat Rev Neurol . 2012 Jan 24. doi: 10.1038/nrneurol.2012.8. [Epub ahead of printPlasma HIV-RNA is the key determinant of long-term antibody persistence following Yellow fever immunization in a cohort of 364 HIV-infected patients. Pacanowski J, Lacombe K, Campa P, Dabrowska M, Poveda JD, Meynard JL, Poirot JL, Fonquernie L, Girard PM.J Acquir Immune Defic Syndr . 2012 Jan 19. [Epub ahead of printSLC7 amino acid transporters of the yellow fever mosquito Aedes aegypti and their role in fat body TOR signaling and reproduction. Carpenter VK, Drake LL, Aguirre SE, Price DP, Rodriguez SD, Hansen IA.J Insect Physiol . 2012 Jan 15. [Epub ahead of printDevelopment of a SYBR green I based RT-PCR assay for yellow fever virus: application in assessment of YFV infection in Aedes aegypti. Dash PK, Boutonnier A, Prina E, Sharma S, Reiter P.Virol J . 2012 Jan 22;9(1):27. [Epub ahead of printAggregate travel vs. single trip assessment: Arguments for cumulative risk analysis. Leder K, Chen LH, Wilson ME.Vaccine . 2012 Jan 9. [Epub ahead of printMethodological issues with the risk of relapse study in patients with multiple sclerosis after yellow Fever vaccination. Pool V, Gordon DM, Decker M.Arch Neurol . 2012 Jan;69(1):144. No abstract available.No evidence of murine leukemia virus-related viruses in live attenuated human vaccines. Switzer WM, Zheng H, Simmons G, Zhou Y, Tang S, Shankar A, Kapusinszky B, Delwart EL, Heneine W.PLoS One . 2011;6(12):e29223. Epub 2011 Dec 22Stability, oviposition attraction, and larvicidal activity of binary toxin from Bacillus sphaericus expressed in Escherichia coli. da Silva Pinto L, Gonçales RA, Conceição FR, Knabah PF, Borsuk S, Campos VF, Arruda FV, Leite FP.Appl Microbiol Biotechnol . 2011 Dec 28. [Epub ahead of printThe phylogeny of yellow fever virus 17D vaccines. Stock NK, Boschetti N, Herzog C, Appelhans MS, Niedrig M.Vaccine . 2012 Feb 1;30(6):989-94. Epub 2011 Dec 23Municipalities of higher vulnerability to Sylvatic Yellow Fever occurrence in the São Paulo State, Brazil. Moreno ES, Barata Rde C.Rev Inst Med Trop Sao Paulo . 2011 Dec;53(6):335-9Fresh, dried or smoked? Repellent properties of volatiles emitted from ethnomedicinal plant leaves against malaria and yellow fever vectors in Ethiopia. Dube FF, Tadesse K, Birgersson G, Seyoum E, Tekie H, Ignell R, Hill SR.Malar J . 2011 Dec 19;10(1):375. [Epub ahead of printElderly subjects have a delayed antibody response and prolonged viraemia following yellow fever vaccination: a prospective controlled cohort study. Roukens AH, Soonawala D, Joosten SA, de Visser AW, Jiang X, Dirksen K, de Gruijter M, van Dissel JT, Bredenbeek PJ, Visser LG.PLoS One . 2011;6(12):e27753. Epub 2011 Dec 7Systems biology in the development of HIV vaccines. Haddad EK, Pantaleo G.Curr Opin HIV AIDS . 2012 Jan;7(1):44-9First
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