Tularaemia

Tularaemia (also known as rabbit fever or deerfly fever) is an infectious disease in ticks and rabbits that is caused by a bacterium (Francisella tularensis). The disease is transmitted by two common ways:

From the bite of an infected tick, deerfly, or mosquito.
When broken skin (cuts, abrasions) comes into direct contact with an infected rabbit carcass

Although uncommon, people also may contract tularaemia by inhaling contaminated dust or by ingesting contaminated meats or water. Human-to-human transmission of tularaemia is uncommon.

Manifestations: Patients will develop:

Ulcer at the site of infection
Swollen lymph nodes
Severe fever

Patients with the less common form of tularaemia, which occurs mainly after inhalation of bacteria, typically experience:

Sudden chills
Fever
Weight loss
Abdominal pains
Tiredness
Headaches.

Patients with this form of tularaemia may develop an unusual pneumonia that can be fatal.

Diagnose and treatment: Blood test demonstrates the diagnose. Treatment with antibiotics is available.

Prevent tularaemia by:

Bite of an infected tick, deerfly, or mosquito
Wear protective rubber gloves when handling rodents

Tularemia Resource:

Infection rates in Glossina morsitans morsitans fed on waterbuck and Boran cattle infected with Trypanosoma congolense.

Acta Trop

Pathogenicity of tsetse-transmitted Trypanosoma congolense for waterbuck (Kobus defassa) and Boran cattle (Bos indicus).

Acta Trop

Genetics of antigenic variation in African trypanosomes.

Res Microbiol

5'-Alkyl-substituted analogs of 5'-methylthioadenosine as trypanocides.

Antimicrob Agents Chemother

Susceptibility of N'Dama and Boran cattle to sequential challenges with tsetse-transmitted clones of Trypanosoma congolense.

Parasite Immunol

Susceptibility of N'Dama and Boran cattle to tsetse-transmitted primary and rechallenge infections with a homologous serodeme of Trypanosoma congolense.

Parasite Immunol

Therapeutic effect of Berenil and Samorin in mice infected with four trypanosome populations isolated from Zambian cattle.

Vet Parasitol

Effect of isometamidium on Trypanosoma congolense infectivity.

Vet Parasitol

Immunohistology of lymph nodes draining local skin reactions (chancres) in sheep infected with Trypanosoma congolense.

J Comp Pathol

An analog of myristic acid with selective toxicity for African trypanosomes.

Science

Mortality rates and population density of tsetse flies correlated with satellite imagery.

Nature

Redox enzyme engineering: conversion of human glutathione reductase into a trypanothione reductase.

Biochemistry

Uganda faces health crisis.

Afr Anal

In vitro simulation of immunosuppression caused by Trypanosoma brucei.

Immunology

A soluble factor from Trypanosoma brucei rhodesiense that prevents progression of activated human T lymphocytes through the cell cycle.

Immunology

[A focus of sleeping sickness without peridomestic Glossina: Kingoyi (Congo)].

Ann Soc Belg Med Trop

Absence of epidemiological inter-relations between HIV infection and African human trypanosomiasis in central Africa.

Trop Med Parasitol

Efficacy of combination of DFMO and diminazene aceturate in the treatment of late stage Trypanosoma brucei brucei infection in rats.

Trop Med Parasitol

Chemotherapy of CNS-trypanosomiasis: the combined use of the arsenicals and nitro-compounds.

Trop Med Parasitol

Investigation of the efficacy of flumethrin pour-on for the control of high tsetse and trypanosomiasis challenge in Kenya.

Trop Med Parasitol

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