Severe Acute Respiratory Syndrome (SARS)

Severe Acute Respiratory Syndrome (SARS), an atypical pneumonia for which cause has not yet been determined. The cause has not been identified, and scientists do not know whether it is a virus or even an infectious agent. Reports to date have been received from Canada, China, Hong Kong Special Administrative Region of China, Indonesia, Philippines, Singapore, Thailand, and Viet Nam.

Manifestations: Main symptoms and signs of SARS which include:

high fever (greater than 38 C)
cough shortness of breath
difficulty breathing

AND one or more of the following:?

close contact with a person who has been diagnosed with SARS
recent history of travel to areas reporting cases of SARS. ?/font>

In the unlikely event of a traveller experiencing this combination of symptoms they should seek medical attention and ensure that information about their recent travel is passed on to the health care staff. Any traveller who develops these symptoms is advised not to undertake further travel until they have recovered. ?/font>

Diagnose and treatment: Diagnose is based on bloodtest. Specific treatment is not available. ?

Vaccine: not available ?

Prevent SARS: Avoid close contact with a person who has been diagnosed with SARS

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Severe Acute Respiratory Syndrome Resource:

A study on pulmonary manifestations in patients with malaria from northwestern India (Bikaner).

J Vector Borne Dis

Eculizumab safely reverses neurologic impairment and eliminates need for dialysis in severe atypical hemolytic uremic syndrome.

Clin Pharmacol

[Mini bronchoalveolar lavage in patients with severe respiratory failure].

Rev Med Chil

Models and mechanisms of acute lung injury caused by direct insults.

Eur J Cell Biol

Acute respiratory distress syndrome with miliary tuberculosis.

Saudi Med J

Alcohol Worsens Acute Lung Injury by Inhibiting Alveolar Sodium Transport through the Adenosine A1 Receptor.

PLoS One

Stability of bovine coronavirus on lettuce surfaces under household refrigeration conditions.

Food Microbiol

Chemically Modified Tetracycline-3 (CMT-3) Prevents ARDS in a Porcine Model of Sepsis + Ischemia/Reperfusion Induced Lung Injury.

Shock

SARS Coronavirus 3b Accessory Protein Modulates Transcriptional Activity of RUNX1b.

PLoS One

Phosphatidylinositol 4-Kinase III beta is required for severe acute respiratory syndrome coronavirus spike-mediated cell entry.

J Biol Chem

Complicated secondary pneumonia after Swine-origin influenza a virus infection in an immunocompetent patient.

Tohoku J Exp Med

First experience with the new portable extracorporeal membrane oxygenation system cardiohelp for severe respiratory failure in adults.

Perfusion

Case report: Increased viral receptor expression associated with high viral load and severe pneumonia in a young patient infected with 2009 H1N1 influenza a with no pre-existing conditions.

J Med Virol

Angiotensin converting enzyme 2 abrogates bleomycin-induced lung injury.

J Mol Med (Berl)

Pathophysiology of Pulmonary Hypertension in Acute Lung Injury.

Am J Physiol Lung Cell Mol Physiol

Recommendations of the Infectious Diseases Work Group (GTEI) of the Spanish Society of Intensive and Critical Care Medicine and Coronary Units (SEMICYUC) and the Infections in Critically Ill Patients Study Group (GEIPC) of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) for the diagnosis and treatment of influenza A/H1N1 in seriously ill adults admitted to the Intensive Care Unit.

Med Intensiva

[Mortality in patients with osteolysis of lymphatic origin: a review of the experience with 54 patients and the literature.]

An Pediatr (Barc)

Mesenchymal stem cells - a promising therapy for Acute Respiratory Distress Syndrome.

F1000 Med Rep

Two palmitylated cysteine residues of the severe acute respiratory syndrome coronavirus spike protein are critical for S-incorporation into virus-like particles, but not for M-S co-localization.

J Gen Virol

Acute Respiratory Distress Syndrome Induced by a Swine 2009 H1N1 Variant in Mice.

PLoS One

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