Plague

Plague is a zoonosis involving rodents and their fleas. The causative agent of plague is a bacterium, Yersinia pestis. Humans are incidental hosts and are usually infected by the bite of rodent fleas. Plague can also be acquired by direct contact with infectious materials or by inhalation of infective respiratory droplets.

Plague continues to be enzootic in wild rodent populations over large rural areas of the Americas, Africa, and Asia, with occasional outbreaks among commensal rodents in villages and small towns. The only continent free of plague is Australia including New Zealand. See map click here

Manifestations: Initial signs and symptoms of plague can be non-specific, with:

Fever
Chills
Malaise
Myalgia
Nausea
Prostration
Sore throat
Headache

Bubonic plague, the most common form, usually presents

painful, swollen lymph nodes (buboes)

Diagnose and treatment: Diagnose is demonstrated by blood test. Treatment is available. . If plague patients are not given specific antibiotic therapy, the disease can progress rapidly to death. About 14% (1 in 7) of all plague cases are fatal.

Prevent plague by:

environmental sanitation
don’t touch rodents.

Plague Resource:

Consensus embedding: theory, algorithms and application to segmentation and classification of biomedical data.

BMC Bioinformatics

Insights from genomic comparisons of genetically monomorphic bacterial pathogens.

Philos Trans R Soc Lond B Biol Sci

Why infest the loved ones - inherent human behaviour indicates former mutualism with head lice.

Parasitology

Evaluation and modification of off-host flea collection techniques used in northwest Uganda: laboratory and field studies.

J Med Entomol

[Value of fleas in the natural foci of plague in the caucasus].

Med Parazitol (Mosk)

Pulmonary infection by Yersinia pestis rapidly establishes a permissive environment for microbial proliferation.

Proc Natl Acad Sci U S A

A fluid biopsy as investigating technology for the fluid phase of solid tumors.

Phys Biol

The piano plague: the nineteenth-century medical critique of female musical education.

Gesnerus

Proposed remedies for some developmental disorders.

Toxicol Ind Health

Hierarchies in Action and Motor Control.

J Cogn Neurosci

The mucoadhesive and gastroretentive properties of hydrophobin-coated porous silicon nanoparticle oral drug delivery systems.

Biomaterials

Evidence of Yersinia pestis DNA from fleas in an endemic plague area of Zambia.

BMC Res Notes

Teaching fearlessness: a manifesto.

Educ Health (Abingdon)

Finally, plague is plague.

Clin Microbiol Infect

The plague of thebes, a historical epidemic in sophocles' oedipus rex.

Emerg Infect Dis

Plague epidemic in the kingdom of naples, 1656-1658.

Emerg Infect Dis

Polymorphisms in the lcrV gene of Yersinia enterocolitica and their effect on plague protective immunity.

Infect Immun

Brain templates and atlases.

Neuroimage

Family Factors in the Development, Treatment, and Prevention of Childhood Anxiety Disorders.

Clin Child Fam Psychol Rev

Out lesbians in nursing: what would florence say?

J Lesbian Stud

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