Myocarditis
Myocarditis is a disorder caused by inflammation of the middle layer of heart muscle. Viral infections such as coxsackie virus, adenovirus, and echovirus are the most common cause. Myocarditis may also occur during or after various viral, bacterial, or parasitic infections. It may also be caused by radiation, exposure to chemicals or medication, or connective tissue diseases. The middle layer of heart muscle becomes inflamed and irritated, causing symptoms similar to a heart attack or even heart failure. It is a fairly uncommon disorder.
Manifestation: Total absence of symptoms is common, but symptoms may include:
Fever Vague chest pain Severe chest pain as in a heart attack Joint pain Palpitations, Rapid heartbeat Fatigue, often from the viral infection Signs and symptoms of congestive heart failure Sudden death (rare) Diagnose and treatment: Tests used in the diagnosis of myocarditis include: ECG showing abnormalities Echocardiogram to observe heart function and rule out clots Biopsy of the heart muscle this test can confirm the diagnosis Cultures (may be performed if infection is suspected as a cause of the disorder) Specific therapy is not available may include analgesics and anti-inflammatory medications (often including steroids) may be used to reduce symptoms. There may be a need to treat arrhythmias with antiarrhythmic medications. Activity may be restricted to bedrest to reduce cardiac workload, and the diet may be salt/sodium restricted.
Myocarditis Resource: Reversible myocarditis after black widow spider envenomation. Dendane T, Abidi K, Madani N, Benthami A, Gueddari FZ, Abouqal R, Zeggwagh AA.Case Report Med . 2012;2012:794540. Epub 2012 Jan 26Hair dye poisoning in Bundelkhand region (prospective analysis of hair dye poisoning cases presented in Department of Medicine, MLB Medical College, Jhansi). Jain PK, Agarwal N, Kumar P, Sengar NS, Agarwal N, Akhtar A.J Assoc Physicians India . 2011 Jul;59:415-9[Leptospirosis and its complications]. [No authors listed]Ter Arkh . 2011;83(11):48-51. Russian.Human immunodeficiency virus & cardiovascular risk. Barbaro G, Barbarini G.Indian J Med Res . 2011 Dec;134(6):898-903Mitral Valve Surgery for Severe Mitral Regurgitation and Dilated Cardiomyopathy-A Bridge to Transplant: Case Report and a Review of Literature. Kobayashi D, Pettersen MD, Walters Iii HL, Aggarwal S.Congenit Heart Dis . 2012 Feb 7. doi: 10.1111/j.1747-0803.2011.00626.x. [Epub ahead of print[Amino acid exchange in paeci lomycosis-complicated echinococcosis]. [No authors listed]Med Parazitol (Mosk) . 2011 Oct-Dec;(4):19-23. Russian.Thrombospondin-2 prevents cardiac injury and dysfunction in viral myocarditis through the activation of regulatory T-cells. Papageorgiou AP, Swinnen M, Vanhoutte D, Vandendriessche T, Chuah M, Lindner D, Verhesen W, de Vries B, D'Hooge J, Lutgens E, Westermann D, Carmeliet P, Heymans S.Cardiovasc Res . 2012 Feb 2. [Epub ahead of printComparison of the Clinical Presentation, Treatment, and Outcome of Fulminant and Acute Myocarditis in Children. Saji T, Matsuura H, Hasegawa K, Nishikawa T, Yamamoto E, Ohki H, Yasukochi S, Arakaki Y, Joo K, Nakazawa M.Circ J . 2012 Feb 4. [Epub ahead of printVaccination with coxsackievirus B3 virus-like particles elicits humoral immune response and protects mice against myocarditis . Zhang L, Parham NJ, Zhang F, Aasa-Chapman M, Gould EA, Zhang H.Vaccine . 2012 Jan 31. [Epub ahead of print[Current problems in the diagnosis and treatment of patients with myocarditis ]. Krawczyk J, Piotrowski G, Gawor R.Pol Merkur Lekarski . 2011 Nov;31(185):265-9. Polish.Subendocardial ischemia and myocarditis in systemic lupus erythematosus detected by cardiac magnetic resonance imaging. Goykhman P, Mehta PK, Minissian M, Thomson LE, Berman DS, Ishimori ML, Wallace DJ, Weisman MH, Shufelt CL, Bairey Merz CN.J Rheumatol . 2012 Feb;39(2):448-50. No abstract available.[Experimental study of MMP-2 inhibitor treatment of experimental autoimmune myocarditis in Lewis rats]. Han LN, Li TL, Zhang YJ, Yang TS, Ding Y.Zhongguo Ying Yong Sheng Li Xue Za Zhi . 2011 Nov;27(4):452-6. Chinese.Drug-Refractory Ventricular Tachycardias Following Myocarditis : Endocardial and Epicardial Radiofrequency Catheter Ablation. Dello Russo A, Casella M, Pieroni M, Pelargonio G, Bartoletti S, Santangeli P, Zucchetti M, Innocenti E, Di Biase L, Carbucicchio C, Bellocci F, Fiorentini C, Natale A, Tondo C.Circ Arrhythm Electrophysiol . 2012 Jan 31. [Epub ahead of printVirus infection of the heart - unmet therapeutic needs. Hazebroek M, Dennert R, Heymans S.Antivir Chem Chemother . 2012 Feb 1. doi: 10.3851/IMP2047. [Epub ahead of printAngina Pectoris with Troponin Increase in Arrhythmogenic Right Ventricle Dysplasia: Case Article and Review of the Literature. Wagner J, Cohen MH, O'Donnell M, Pauliks LB.Pediatr Cardiol . 2012 Jan 31. [Epub ahead of print[Sudden cardiac death : Selected forensic aspects.] Bajanowski T, Püschel K, Dettmeyer R.Pathologe . 2012 Feb 1. [Epub ahead of print] German.Aborted sudden death from Epstein-Barr myocarditis . Farina A, Maggiolini S, Di Sabato M, Gentile G, Meles E, Achilli F.J Cardiovasc Med (Hagerstown) . 2011 Nov;12(11):843-7. No abstract available.RNA-Seq Based Transcriptional Map of Bovine Respiratory Disease Pathogen "Histophilus somni 2336". Kumar R, Lawrence ML, Watt J, Cooksey AM, Burgess SC, Nanduri B.PLoS One . 2012;7(1):e29435. Epub 2012 Jan 20Resuscitation of Non-postcardiotomy Cardiogenic Shock or Cardiac Arrest with Extracorporeal Life Support: The Role of Bridging to Intervention. Wu MY, Lee MY, Lin CC, Chang YS, Tsai FC, Lin PJ.Resuscitation . 2012 Jan 20. [Epub ahead of printBeneficial effects of edaravone, a novel antioxidant, in rats with dilated cardiomyopathy. Arumugam S, Thandavarayan RA, Veeraveedu PT, Nakamura T, Arozal W, Sari FR, Giridharan VV, Soetikno V, Palaniyandi SS, Harima M, Suzuki K, Nagata M, Kodama M, Watanabe K.J Cell Mol Med . 2012 Jan 23. doi: 10.1111/j.1582-4934.2012.01526.x. [Epub ahead of printFirst
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