Chlamydia pneumoniae

The bacteria Chlamydia pneumoniae.is the cause of this disease. The disease is transmitted from person to person by respiratory secretions. Reinfection throughout life appears to be common. C. pneumoniae infection may be associated with atherosclerotic vascular disease. Associations with Alzheimer’s disease, asthma, and reactive arthritis have been proposed.

Manifestations: Pneumonia or bronchitis, gradual onset of cough with little or no fever.

Diagnose and treatment: Diagnose is based on bloodtest . Treatment with antibiotics is available.

Vaccine: Not available

Prevention: There are no known methods to prevent infection or possible sequelae

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Chlamydiapneumoniae Resource:

Treatment of chlamydial infections.

Expert Opin Pharmacother

Genomic screening for Chlamydophila pneumoniae-specific antigens using serum samples from patients with primary infection.

FEMS Microbiol Lett

Potential association of Helicobacter cinaedi with atrial arrhythmia and atherosclerosis.

Microbiol Immunol

Lack of association of conjunctival MALT lymphoma with Chlamydiae or Helicobacter pylori in a cohort of Chinese patients.

Med Sci Monit

NLRP3 Inflammasome is a Target for Development of Broad-Spectrum Anti-Infective Drugs.

Antimicrob Agents Chemother

Antimicrobial activity of the novel pleuromutilin antibiotic BC-3781 against organisms responsible for community-acquired respiratory tract infections (CARTIs).

J Antimicrob Chemother

Structural analysis and serological test of arginine periplasmic binding protein 2 from Chlamydophila pneumoniae.

Biochem Biophys Res Commun

Chlamydophila pneumonia inhibits the corticosteroid-induced suppressions of metalloproteinase-9 and tissue inhibitor metalloproteinase-1 secretion by human peripheral blood mononuclear cells.

J Med Microbiol

Rac1 Regulates the NLRP3 Inflammasome Which Mediates IL-1beta Production in Chlamydophila pneumoniae Infected Human Mononuclear Cells.

PLoS One

Structural Characterization of a Novel Chlamydia pneumoniae Type III Secretion-Associated Protein, Cpn0803.

PLoS One

Heterocyclic urea derivatives and methods of use thereof (WO2010142978).

Expert Opin Ther Pat

Chlamydia infection status, genotype, and age-related macular degeneration.

Mol Vis

The Molecular Anatomy of Human Hsp60 and its Similarity with that of Bacterial Orthologs and Acetylcholine Receptor Reveal a Potential Pathogenetic Role of Anti-Chaperonin Immunity in Myasthenia Gravis.

Cell Mol Neurobiol

Lack of effective anti-apoptotic activities restricts growth of parachlamydiaceae in insect cells.

PLoS One

Successful treatment of Chlamydophila pneumoniae acute respiratory distress syndrome with extracorporeal membrane oxygenator: a case report and diagnostic review.

J Med Case Reports

Detection of IgM and IgG antibodies to Chlamydophila pneumoniae in pediatric community-acquired lower respiratory tract infections.

Indian J Pathol Microbiol

Chlamydophila pneumoniae phospholipase D (CpPLD) drives Th17 inflammation in human atherosclerosis.

Proc Natl Acad Sci U S A

Chlamydophila pneumoniae Infection Induced Nodular Vasculitis.

Case Rep Dermatol

Flotillin-1/reggie-2 contributes to Chlamydia pneumoniae growth and associates with bacterial inclusion.

Infect Immun

Chlamydophila pneumoniae Infection Induces Alterations in Vascular Contractile Responses.

Am J Pathol

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