Ascariasis

Ascariasis lumbricoides is the most common human worm infection. Ascarid eggs are found in the soil. Infection occurs when a person ingests infective ascarid eggs. Once in the stomach, larvae hatch from the eggs. The larvae are carried through the lungs then to the throat where they are then swallowed. Once swallowed, they reach the intestines and develop into adult worms. Adult female worms lay eggs that are then passed in faeces; this cycle will take between 2-3 months.

Occurrence: Infection occurs worldwide and is most common in tropical and subtropical areas where sanitation and hygiene are poor. Children are infected more often than adults are.

Manifestations: Most people have no symptoms. If you are heavily infected, you may have Abdominal pain. cough, while the immature worms migrate through the lungs, difficulty breathing. Intestines may become blocked.

Diagnose and treatment: Diagnose is based on stool samples for testing. There is no blood test used to diagnose an ascarid infection. Treatment is effective with antibiotics.

Vaccine: Not available

Prevent infection with ascarids by:

Avoid contacting soil that may be contaminated with human faeces.
Do not defecate outdoors. Dispose of diapers properly.
Wash hands with soap and water before handling food.
When travelling to countries where sanitation and hygiene are poor, avoid water or food that may be contaminated.
Wash, peel or cook all raw vegetables and fruits before eating.

Ascariasis Resource:

Increase in acanthamoeba keratitis may be associated with use of multipurpose contact lens solution.

BMJ

Effect of bovine lactoferrin in a therapeutic hamster model of hepatic amoebiasis.

Biochem Cell Biol

Leptin Protects Host Cells from Entamoeba histolytica Cytotoxicity by a STAT3-Dependent Mechanism.

Infect Immun

Cloning, expression and evaluation of the efficacy of a recombinant Entamoeba histolytica cysteine proteinase (EhCP4) antigen in minipig.

Exp Parasitol

Establishment of a transient transfection system and expression of firefly luciferase in Entamoeba invadens.

Mol Biochem Parasitol

Predictive value of endoscopic findings in the diagnosis of active intestinal amebiasis.

Endoscopy

Primary amoebic meningo-encephalitis due to Naegleria fowleri.

J Indian Med Assoc

A meta-analysis and systematic review on the effect of probiotics in acute diarrhea.

Inflamm Allergy Drug Targets

Confocal microscopy.

Ophthalmology

Porcine colon explants in the study of innate immune response to Entamoeba histolytica.

Vet Immunol Immunopathol

Catheter drainage versus needle aspiration in management of large (>10 cm diameter) amoebic liver abscesses.

ANZ J Surg

Acanthamoeba keratitis--a diagnostic challenge.

Clin Lab Sci

Residual amoebic liver abscess in a prospective renal transplant recipient.

Saudi J Kidney Dis Transpl

Amoebicidal activity of the rhizomes and aerial parts of Allium sivasicum on Entamoeba histolytica.

Parasitol Res

Evaluation of amoebicidal potential of Paneth cell cryptdin-2 against Entamoeba histolytica.

PLoS Negl Trop Dis

Towards the establishment of a porcine model to study human amebiasis.

PLoS One

Evaluation of the efficacy of a recombinant Entamoeba histolytica cysteine proteinase gene (EhCP5) antigen in Minipig.

Exp Parasitol

Twitter and mobile technology as diagnostic aids in the Democratic Republic of Congo.

Am Surg

The impact of man on the occurrence of the pathogenic free-living amoeboflagellate Naegleria fowleri.

Future Microbiol

Microsporidia and Acanthamoeba: the role of emerging corneal pathogens.

Eye (Lond)

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