Amoebiasis

Amoebiasis is a disease caused by a one-celled parasite called Entamoeba histolytica : Most of the infected people are healthy carriers. It means that they do not have symptoms of the infection.

Manifestation: Nearly about one in 10 people who are infected with E. histolytica become sick. The symptoms often are quite mild and can include loose stools, stomach pain, and stomach cramping. Amoebic dysentery is a severe form of amoebiasis associated with stomach pain, bloody stools, and fever. Rarely, E. histolytica invades the liver and forms an abscess. Even less commonly, it spreads to other parts of the body, such as the lungs or brain.

Occurrence: The infection occurs worldwide. In developing countries with poor sanitary conditions nearly 50% of the people are infected. The occurrence of disease with abscesses is limited to infections in:

Mexico
South-America, western part
South Asia
Western and south-western Africa

Transmission: Infection is spread from person to person in case of poor sanitary conditions.

Diagnose and treatment: Diagnose is done by demonstrating amoebae in stools. Treatment is possible with good results.

Prevent amoebiasis by:

Don’t put anything into your mouth that has touched the stool of a person who is infected with E. histolytica.

Don’t swallow something, such as water or food that is contaminated with E. histolytica.

Don’t touch and bring to your mouth cysts (eggs) picked up from surfaces that are contaminated with E. histolytica.

Avoid sexual practices that allow faecal-oral contact.

Amoebiasis Resource:

[Experimental teaching program on cooperation between Â«SapienzaÂ» University of Rome and the University Hospital "Le Bon Samaritain" in N'Djamena, Chad].

Ann Ital Chir

Development of thermostabilised one-step nested tetraplex PCR assay for simultaneous identification and differentiation of Entamoeba spp., Entamoeba histolytica and Entamoeba dispar from stool samples.

J Med Microbiol

Amebiasis deaths in the United States.

Am J Trop Med Hyg

Spectrum of imported infectious diseases among children and adolescents returning from the tropics and subtropics.

J Travel Med

[Microscopic diagnosis of amebiasis: an obsolete method but necessary in the developing world].

Invest Clin

Risk factors for intestinal invasive amebiasis in Japan, 2003-2009.

Emerg Infect Dis

An Unusual Cause of Unilateral Hydronephrosis: Invasive Colonic Amebiasis.

Ren Fail

Entamoeba histolytica Cell Surface Calreticulin Binds Human C1q and Functions in Amebic Phagocytosis of Host Cells.

Infect Immun

Oral lactoferrin treatment resolves amoebic intracecal infection in C3H/HeJ mice.

Biochem Cell Biol

Control of Entamoeba histolytica Adherence Involves Metallosurface Protease 1, an M8 Family Surface Metalloprotease with Homology to Leishmanolysin.

Infect Immun

Stable transfection and continuous expression of heterologous genes in Entamoeba invadens.

Mol Biochem Parasitol

[Ultrasonographic features of liver abscess based on a 58-case series in Cameroon].

Med Trop (Mars)

[Pseudotumoral appearance of hepatic amebiasis].

Med Trop (Mars)

Atrial flutter and pericarditis--a rare complication of right lobe amoebic liver abscess.

Med J Malaysia

Biochemical, mutational and in silico structural evidence for a functional dimeric form of the ornithine decarboxylase from Entamoeba histolytica.

PLoS Negl Trop Dis

Endoplasmic reticulum stress-sensing mechanism is activated in Entamoeba histolytica upon treatment with nitric oxide.

PLoS One

Novel transmembrane receptor involved in phagosome transport of lysozymes and Î²-hexosaminidase in the enteric protozoan Entamoeba histolytica.

PLoS Pathog

Pleural empyema secondary to rupture of amoebic liver abscess.

Intern Med

Isolation and identification of Acanthamoeba species from thermal spring environments in southern Taiwan.

Exp Parasitol

Virtual screening, identification and in vitro testing of novel inhibitors of O-acetyl-L-serine sulfhydrylase of Entamoeba histolytica.

PLoS One

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