Anterior uveitis after treatment of hepatitis C with alpha interferon: the recurrence of a previous inflammatory process due to presumed ocular toxocariasis.

Authors: Damasceno EF,Damasceno NA,
Address:
Journal: Ocul Immunol Inflamm.

Publication: 2012 Feb;20(1):53-5. doi: 10.3109/09273948.2011.615448.

abstract

OBJECTIVE:

To report a case of recurrent unilateral presumed ocular toxocariasis after treatment of hepatitis C.

DESIGN:

Case study.

METHODS:

Clinical findings, ultrasonography, computed tomography, and serological tests were performed. Once diagnosis was made, effective treatment was administered.

RESULTS:

A 46-year-old woman with a long history of decreased unilateral visual acuity presented with Anterior uveitis after the use of interferon alpha and ribavirin for treatment of hepatitis C. A biomicroscopic examination revealed active anterior uveitis, with ultrasonography and computed tomography demonstrating a central granuloma due to partially calcified toxocariasis. After treatment with corticosteroids and cycloplegics, the symptoms were alleviated.

CONCLUSION:

immunostimulation could cause a relapse of the inflammatory reaction found in uveitis due to toxocariasis.

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