A specific diagnostic antigen of Echinococcus granulosus with an apparent molecular weight of 8 kDA.

Authors: Maddison SE,Slemenda SB,Schantz PM,Fried JA,Wilson M,Tsang VC,
Address: Division of Parasitic Diseases, Centers for Disease Control, Atlanta, Georgia.
Journal: Am J Trop Med Hyg.

Publication: 1989 Apr;40(4):377-83.

abstract

An Echinococcus antigen with an apparent molecular weight of 8 kDA was identified as diagnostically important. An immunoblot assay using this antigen was 91% sensitive for surgically confirmed Echinococcus granulosus hydatid disease of the liver. specificity was 100% for echinococcosis. Marked cross-reactivity was observed with serum specimens from patients with E. multilocularis and E. vogeli infections. The 8 kDa component was not related to the widely recognized echinococcus antigen 5.

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