A plethora of Plasmodium species in wild apes: a source of human infection?

Authors: Rayner JC,Liu W,Peeters M,Sharp PM,Hahn BH,
Address: Malaria Programme, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK. julian.rayner@sanger.ac.uk
Journal: Trends Parasitol.

Publication: 2011 May;27(5):222-9. doi: 10.1016/j.pt.2011.01.006. Epub 2011 Feb 25.
Free Text: A plethora of Plasmodium species in wild apes: a source of human infection?

abstract

Recent studies of captive and wild-living apes in Africa have uncovered evidence of numerous new Plasmodium species, one of which was identified as the immediate precursor of human Plasmodium falciparum. These findings raise the question whether wild apes could be a recurrent source of Plasmodium infections in humans. This question is not new, but was the subject of intense investigation by researchers in the first half of the last century. Re-examination of their work in the context of recent molecular findings provides a new framework to understand the diversity of Plasmodium species and to assess the risk of future cross-species transmissions to humans in the context of proposed malaria eradication programs.

Related Articles
Review Ape Plasmodium parasites as a source of human outbreaks.
Clin Microbiol Infect. 2012
Review Ape Plasmodium parasites as a source of human outbreaks.
Duval L, Ariey F. Clin Microbiol Infect. 2012 Jun; 18(6):528-32. Epub 2012 Mar 22.
Wild chimpanzees infected with 5 Plasmodium species.
Emerg Infect Dis. 2010
Wild chimpanzees infected with 5 Plasmodium species.
Kaiser M, Löwa A, Ulrich M, Ellerbrok H, Goffe AS, Blasse A, Zommers Z, Couacy-Hymann E, Babweteera F, Zuberbühler K, et al. Emerg Infect Dis. 2010 Dec; 16(12):1956-9.
Origin of the human malaria parasite Plasmodium falciparum in gorillas.
Nature. 2010
Origin of the human malaria parasite Plasmodium falciparum in gorillas.
Liu W, Li Y, Learn GH, Rudicell RS, Robertson JD, Keele BF, Ndjango JB, Sanz CM, Morgan DB, Locatelli S, et al. Nature. 2010 Sep 23; 467(7314):420-5.
Malaria's primate links.
Curr Biol. 2009
Malaria's primate links.
Williams N. Curr Biol. 2009 Aug 25; 19(16):R668-9.
Review A fresh look at the origin of Plasmodium falciparum, the most malignant malaria agent.
PLoS Pathog. 2011
Review A fresh look at the origin of Plasmodium falciparum, the most malignant malaria agent.
Prugnolle F, Durand P, Ollomo B, Duval L, Ariey F, Arnathau C, Gonzalez JP, Leroy E, Renaud F. PLoS Pathog. 2011 Feb; 7(2):e1001283. Epub 2011 Feb 24.
Anopheles moucheti and Anopheles vinckei Are Candidate Vectors of Ape Plasmodium Parasites, Including Plasmodium praefalciparum in Gabon.
PLoS One. 2013
Anopheles moucheti and Anopheles vinckei Are Candidate Vectors of Ape Plasmodium Parasites, Including Plasmodium praefalciparum in Gabon.
Paupy C, Makanga B, Ollomo B, Rahola N, Durand P, Magnus J, Willaume E, Renaud F, Fontenille D, Prugnolle F. PLoS One. 2013; 8(2):e57294. Epub 2013 Feb 20.
Individual variation in levels of haptoglobin-related protein in children from Gabon.
PLoS One. 2012
Individual variation in levels of haptoglobin-related protein in children from Gabon.
Imrie HJ, Fowkes FJ, Migot-Nabias F, Luty AJ, Deloron P, Hajduk SL, Day KP. PLoS One. 2012; 7(11):e49816. Epub 2012 Nov 20.
Review Resistance to malaria in humans: the impact of strong, recent selection.
Malar J. 2012
Review Resistance to malaria in humans: the impact of strong, recent selection.
Hedrick PW. Malar J. 2012 Oct 22; 11:349. Epub 2012 Oct 22.

To top • Home

TraveldoctorOnline 2001 • Disclaimer • webmaster

The contents within traveldoctoronline are presented only for informational purposes and cannot substitute for professional health care or any other medical treatment.All users of this website with health problems should be oblige always to consult their medical doctor before starting any treatment.